A Gulfstream took off from Rochester, USA, and was slowly heading towards the capital of China.

on the plane.

Yuan Chaomin and others never imagined that this time they could take a private jet when they came back. There were everything on the plane, and there were things that shouldn't be there.

A caring stewardess sent a quilt to the warm-hearted, and the chairs on the plane can also be used as beds.

There are also professional chefs who prepare meals.

And all of this was brought by Chen Nan.

The plane belongs to Miao's family. The Miao family's industries spread all over the world, and they often need to travel internationally, so it's normal to have a plane at home.

And this Gulfstream was also custom-made by Mr. Miao Dingfu.

The degree of luxury is naturally extraordinary.

Lu Shouyue looked at Chen Nan with a smile: "Xiao Chen, this time...we will enjoy happiness with you!"

Yuan Chaomin glanced at Yang Fupeng, who was eating happily there, and smiled: "It's Director Yang who really eats and drinks with him, and finally gains the most!"

"Look, there's nothing wrong with that!"

Yuan Chaomin's words made everyone laugh immediately.

Instead of paying attention, Yang Fupeng said with a smile: "Old Yuan, don't tell me, I really feel at ease!"

"Why……"

"I now understand why people like to hug their thighs."

"This guy, you don't have to work hard at all, just lay down and win!"

"Hahaha……"

"I'm not afraid of your jokes. I, Yang Fupeng, have participated in several world cancer drug conferences, and I have never obtained authorization for more than ten drugs."

"Tsk tsk tsk, this time, it can be said that I have a lot of money!"

"Why……"

"All of this is due to Professor Chen!"

"I... didn't do anything!"

"It's because I was brought by Professor Chen's ticket. It's that simple. People don't look at the monk's face to see the Buddha's face!"

Hearing these words, everyone nodded in agreement.

This time!

Chen Nan's icariin extract really shined in this international conference.

With this, Annan Pharmaceutical has instantly become a favorite in the eyes of many international capitals.

but!

Compared with icariin, the most heart-breaking bomb in this new drug conference is not any drug, but a "dumb bomb!"

What does that mean?

It is the third generation sequencing technology!

Precision medicine is now the most popular technology in the world.

The core of precision medicine lies in this genetic testing.

NMPA company has made a lot of money in recent years, and its social status and industry positioning have been constantly praised. Even the "Lancet" called next-generation sequencing a phased victory in changing the development of tumor diseases!

And the reason is very simple, because this second-generation sequencing has brought medical care into the era of genes.

Subsequent targeted drugs will spring up like mushrooms, the first generation, second generation, third generation...

Obviously, after opening the door to genes, targeted drugs have also entered a crazy development stage.

And those who benefit the most are also these large foreign pharmaceutical companies.

And China!

Obviously did not keep up with this wave of rides.

It is undeniable that the development of our medical technology is indeed backward.

But... can we really not make a single targeted drug?

This is obviously not realistic!

There are too many reasons behind this.

In fact, the development of targeted drugs is like this, and so is the development of society!

Rule makers naturally enjoy the highest priority benefits.

At this time, Yuan Chaomin couldn't help but glanced at Chen Nan worriedly, and said earnestly:

"Chen Nan, do you really have the third-generation sequencing technology?"

After he finished speaking, he realized that what he said was inappropriate, and quickly explained: "I didn't mean to probe your news and secrets, but... this matter is too important!"

"Genetic engineering is a subject that has been booming in our country, but it has lagged behind the international level in recent years!"

"If... if... you really have three generations of sequencing!"

"I mean……"

"We may really usher in a fast track for the development of oncology medicine!"

Yuan Chaomin was naturally extremely excited.

As the reformer of liver cancer surgery in China, the doctor with the largest number of liver cancer operations in the world, and the doctor with the highest success rate of treatment, as the academic successor of Mr. Wu, Yuan Chaomin has devoted his whole life to this position.

He has seen too many pictures of patients on the hospital bed, waiting for medicine.

I have also seen many tragic experiences of returning to poverty due to illness and becoming impoverished due to illness.

I have also seen too many greedy faces of capital. In the hands of those people, medicine is undoubtedly a tool for making money.

Chen Nan glanced at Yuan Chaomin. He was very grateful to Director Yuan. When he was unable to attend the meeting, Director Yuan was the first to stand up.

A Chinese oncologist who is full of passion and iron bones.

Chen Nan knew very well that the other party wanted to work hard for the development of Chinese oncology medicine.

but……

There are some things that cannot be said before the time comes!

Chen Nan could only say ambiguously: "Hey...Director Yuan, what should I say?"

"I know something about three-generation sequencing."

"But... I can't clearly grasp such a technique."

"You know, I practice Chinese medicine."

After hearing this, Yuan Chaomin sighed helplessly.

"Hey……"

"I'm greedy!"

"Actually, you are already very powerful."

"This time, the new drug display of icariin allowed us to win the most anticipated drug award."

"Let's not say we have won this award, we have never seen it before!"

"Hey……"

"Really, we're all very happy."

"Enough!"

"It's just... I'm a little worried about one thing."

"You said, this time, will the NMPA company treat our domestic drug testing unfairly because of your remarks?"

"At the beginning, our Food and Drug Administration also spent a lot of effort in order to obtain the certification of NMPA."

"Hey……"

"And, in fact, your medicine is also a little troublesome."

"Although it is the most anticipated drug, there is a big hidden danger, which is the targeted drug standard certified by NMPA!"

"Right now, everyone has not put forward their opinions, or has other ideas, and they are flattering you because they are worried that you have three generations of sequencing!"

"But... if there really isn't one."

"I think...you need to prepare early."

"If your drug cannot be sequenced by NMPA, you will encounter a lot of trouble for the internationalization of this drug!"

After Yuan Chaomin said these words, Lu Shouyue on the side also nodded.

"yes!"

"If the other party knows that we don't have third-generation sequencing."

"That group of people... are not good people."

"The NMPA sequencing company is not kidding, they hold grudges very much. I remember that in the early years, a country rejected the application of the NMPA company. Later... After the NMPA developed, it directly failed to pass this country. certification!"

Chen Nan could hear the worry in everyone's heart. They were worried that the lie would be exposed one day.

It's really that day...

But it didn't end well.

It will even backfire!

Chen Nan said with a smile at this time: "Director Yuan, Professor Lu, although I said that I have not mastered such a technology!"

"But it doesn't mean that others have not mastered it!"

"Third-generation sequencing is about to mature."

"It won't be long!"

While speaking, Chen Nan was also full of confidence.

Upon hearing Chen Nan's words, Yuan Chaomin and the others suddenly changed their expressions, and looked at Chen Nan in unison.

"Really?"

Chen Nan smiled and nodded: "This, you can have it!"

In a word, everyone's eyes widened.

Yang Fupeng couldn't care less about enjoying the skills of a top Michelin chef, he opened his mouth wide and couldn't help but say, "Professor Chen, you mean...we..."

Yuan Chaomin glared directly at the other party, and looked at Chen Nan with excitement: "Understood!"

"We understand!"

"This, can't say!"

Chen Nan: ...

He saw that everyone followed Yuan Chaomin's example and nodded, saying they understood.

I can't help but feel a little helpless.

To be honest, Chen Nan has many things on his mind right now.

Firstly, it was Master Lu's body that made Chen Nan unhappy.

The second is how the development of third-generation sequencing technology will drive the development of domestic tumors and how to promote the development of traditional Chinese medicine.

Chen Nan hasn't thought through these things yet.

Before leaving today, Chen Nan completely offended Tashi, the senior executive of the NMPA company.

but……

how to say?

There are things he has to do.

After all, there is a battle with NMPA, precision medicine in the world, and foreign targeted drugs.

Bright sword, sooner or later.

It is also something that must be done.

He now has some preliminary ideas.

He also communicated with Mr. Miao Dingfu.

He wants to use Miao Lao's disease as a case to write a professional paper on the immature performance of next-generation sequencing technology.

Moreover, this paper must be published in a journal of the "Lancet" level, or a key journal in the field of tumors.

received widespread attention.

But, now is not the time.

He needs to wait for the publication of the "Proceedings of World Cancer New Drug Conference".

After the new drug launch, the World Cancer Society will organize it into a journal based on the content of the meeting.

The release of this journal will naturally lead to an upsurge in the analysis of next-generation sequencing technology in the field of tumors.

And at that time, it was his own opportunity.

Mr. Miao Dingfu is still very important, he gave Chen Nan a promise.

It will definitely help Chen Nan fuel the flames.

This made Chen Nan realize that it was the right time to meet Mr. Miao this time.

...

...

And at this time!

With Chen Nan's departure, the speculation about the third-generation sequencing in Europe and the United States has entered a special stage.

To know!

Targeted drugs rely on genetic engineering.

Next-generation sequencing for genetic testing.

They are all authorizing technical support, and NMPA, as the world's largest genetic testing company, can be said to have a wide range of rights.

Not to mention the general pharmaceutical companies, even the food and drug regulatory authorities in many countries have to give a little bit of thin air.

no way!

Since the development of precision medicine, targeted drugs have become a synonym for NMPA.

Without other people's certification, the US FDA will not grant a license.

What do you take to enter the international market.

As we all know, many countries in the world do not have their own independent food and drug supervision and management departments, and many countries use the standards of the US FDA.

Therefore, NMPA has entered a special period since 2010.

At this time, NMPA urgently held a meeting.

The discussion was about the feasibility of the third-generation sequencing technology, and whether Chen Nan had mastered the important information of the third-generation sequencing.

This is the soul of NMPA's development.

This moment.

The meeting room was silent, no one spoke, but a meeting record was being played.

This is exactly what Chen Nan said at the World Cancer Drug Conference.

At the meeting site, there were nearly 30 people, all of whom were senior managers and core technical backbones of NMPA.

a long time!

Wait until the video ends.

A very gentle-looking middle-aged man headed by looked at a group of technical backbones and asked:

"Professor Merck, this is all Chen Nan's remarks about the third-generation sequencing!"

"What do you think?"

When Merck heard the sound, his mind was heavy and complicated.

"Mr. Bird, to be honest... I'm also a little unsure."

"From a technical point of view, third-generation sequencing needs to be based on second-generation sequencing to solve many problems, which we have not solved so far."

"Although there are many genetic testing companies in the world,... I believe that everyone's progress will not be too different!"

"So, I think it is difficult for the opponent to make a breakthrough in terms of technology!"

Having said that, Merck sighed: "But!"

"However, I feel that the other party seems to know the three generations of technology like the palm of his hand!"

"From the other party's remarks, and from the other party's use of the third-generation sequencing technology, and many other aspects."

"But I feel that the other party seems to have mastered such a technique!"

"So, to be honest, I can't guarantee it myself."

Byrd heard the sound, his face remained unchanged.

The NMPA company may seem huge, but in fact, it is still eating its money these years.

Their free ride is that after Obama went up, he proposed precision medicine.

And it just so happens!

Obama attaches great importance to medical reform and the development of the medical field.

As an established genetic testing company, NMPA maintained in-depth cooperation with the FDA at that time.

Then!

With the expansion of Obama's influence, precision medicine has also become the object of capital competition.

NMPA, which cooperates with the FDA, also took advantage of the trend.

Only then did the subsequent development occur.

Byrd is clear on that point.

Currently!

Targeted drugs have developed to three generations!

Problems with third-generation targeted drugs have also begun to emerge.

The drug resistance of the third-generation targeted drugs has reached an embarrassing situation.

However, with the fourth generation of targeted drugs, no new clues could be found at all.

This is obviously a problem in the field of genetic engineering.

But why!

Next-generation sequencing also encountered bottlenecks.

So, there is an inextricable relationship between the two.

Just at this time, the information of the third generation sequencing was revealed by Chen Nan.

nature!

Bird is very clear that once this issue of "World Oncology New Drug Conference Proceedings" comes out, this next-generation sequencing will definitely become a hot topic.

They can't let this happen.

Therefore, they began to collect information and investigate on the same day.

After listening to Merck's words, Bird said to the crowd:

"What do you think of this matter?"

soon!

Everyone started to speak.

"I don't think that Chen Nan has mastered the third-generation sequencing. According to my investigation of Chen Nan, I found that the other party is only quite accomplished in the field of traditional Chinese medicine, but... genetic engineering is obviously not the other party's specialty, and the Chen family is not in this field. research basis.

Three generations of sequencing, it is impossible to come out so soon!

This is just alarmist talk! "

Soon someone stood up and said, "That's right, I even think that this is Chen Nan's retaliatory behavior against our company."

"He stood up because we canceled the other party's certification."

"We all know the difficulty of three-generation sequencing."

"That's right, I also think so. Through my investigation, I didn't find that other well-known genetic testing companies have three-generation sequencing technology and progress!"

...

All of a sudden, various departments began to speak.

Bird heard the sound and began to think.

At this time, a person suddenly said: "President, I think, right now, one thing should be clarified."

"That is, this is a domestic matter in China, or a matter for Chen Nan alone."

"In recent years, China's genetic engineering has developed rapidly, and so has genetic testing."

"If it is an official action, we have to pay attention."

"However, if it's a personal behavior, I think we should put pressure on the other party to make Chen Nan apologize!"

"And, this is also a temptation!"

"It's impossible to believe things that are based on rumors and shadows."

Byrd pondered for a long time, then nodded slowly.

"Is there any more?"

At this time, suddenly a person spoke.

Tashi held a report with a complex expression on his face, to be honest...

He really didn't want to talk about these things.

but!

At this time, he had to say.

"President, I have some information here."

"Yesterday, Chen Nan went to treat Mr. Miao Dingfu, who is also the executive chairman of the American Chinese General Chamber of Commerce, Miao Dingfu!"

"I went too."

"At that time, Chen Nan firmly believed that Mr. Miao was in a precancerous state."

"However, our test results are not the case."

"And Chen Nan said at the time that the error and error rate of our next-generation sequencing are high, which is the limitation of the second-generation sequencing itself."

"He said it could be done if we did it a few more times."

"So... I started the test yesterday and overnight."

"But... the result is here!"

Suddenly, an engineer stood up and said, "Miao Dingfu? I did his test!"

"I even did it three times and it was normal."

"There is no possibility of a precancerous state!"

"This is Chen Nan's nonsense."

Tashi sighed helplessly. To be honest, he didn't want to believe the result in his hands.

However, the facts are in front of us.

Everything that happened was exactly as predicted by Chen Nan, so he had to doubt it.

even……

A little fear and uneasiness also sprouted in Tashi himself.

He always felt that Chen Nan was not trying to scare people, let alone aim at nothing.

Seeing this, Bird said to Tashi: "Professor Tashi, what happened?"

Tashi couldn't help shaking his head: "Yesterday, Chen Nan said that if we want to detect it, we need to conduct more than ten tests."

"I don't believe in evil!"

"But we have to take it to heart, so yesterday we worked overtime and tested more than a dozen times in a row!"

"After seven in a row, the information about the precancerous status finally emerged."

"However, after the next eleven times, it appeared again!"

"This...is...a horrible thing."

"So, I can't guarantee whether Chen Nan really understands the second-generation sequencing or the third-generation sequencing!"

"But... what he said is too true."

"I think we should take it seriously."

Sure enough, following Tashi's words, the room fell silent, followed by frantic discussions and support.

Enduring!

And half an hour later, Bird suddenly said: "Contact Morton, the president of China, and negotiate with the other party!"

"Don't rule out preparing to put pressure on the opponent!"

After Byrd finished speaking, there was a bit of coldness in his eyes.

This time!

It must be done.

The plane will arrive in China in two hours.

Chen Nan and the others entered another long night in the long night.

but……

Everyone was very excited, and many people fell asleep.

Because after landing today, they want to bring such good news home!

This is going to be something that a lot of people will be excited about.

Even, many people are ready to get drunk tonight.

...

However, at this moment.

A serious meeting is underway!

The representative of NMPA in China had already met Qin Shiming at this time.

In the huge office, a conversation is going on at this time.

Here, headed by Qin Shiming, there is Liao Wenkai who takes medicine, and many other experts and persons in charge.

On the opposite side is Morton, the president of NMPA in China, and some senior executives of NMPA.

Morton looked at Qin Shiming and said seriously:

"Mr. Qin, we are old friends."

"NMPA has been acting as an agent for Huaxia's targeted gene testing for many years."

"In China, with our help and technical support, good results have been achieved in the field of precision medicine."

"And now, we have to consider a problem, which is Professor Chen Nan's problem!"

"This time, Chen Nan repeatedly made unreasonable remarks about our NMPA company at the World Cancer Drug Conference."

"And making improper remarks about our company's next-generation sequencing and many other things has already had a very bad impact on our company."

"For this meeting, I am representing the headquarters of the NMPA company, and I will have an official conversation with Mr. Qin!"

"We want to know whether this is the meaning of Professor Chen Nan alone, or he represents the meaning of Huaxia!"

When Morton said these words, he was straight to the point, without the slightest bit of politeness or hypocrisy!

Or……

In the eyes of everyone in Morton, they didn't take Qin Shiming and others seriously.

Qin Shiming glanced at Liao Wenkai, pursed his lips, and took a sip of tea from his teacup.

Liao Wenkai acted vigorously and asked directly:

"Is there a difference?"

Morton smiled and said, "Of course!"

"Mr. Liao, we have cooperated for so many years."

"If it's Chen Nan's problem, I hope you can order him to issue an apology statement."

"We can not pursue its legal responsibility!"

"but……"

"If it is your arrangement and request, if Chen Nan represents Huaxia, this is another solution."

Hearing Morton's words, many people in the room looked ugly.

They are very clear that these words already carry the meaning of threat.

as expected!

Liao Wenkai slapped the table excitedly: "Hehe!"

"What are you going to do?"

Qin Shiming stopped Liao Wenkai, signaling to calm down.

He thought clearly, since the other party came to the door without waiting for Chen Nan to get off the plane, he was obviously flustered.

This is to borrow a knife to kill someone!

but!

Was Qin Shiming threatened to grow up?

Thinking of this, he couldn't help but smile contemptuously.

"Hehe, President Morton, is it possible that you want to cancel the cooperation with us?"

Morton smiled and said, "Of course not!"

"It's been a pleasure working with us."

"Isn't it? Mr. Qin!"

"I just don't want to affect our cooperation because of Chen Nan's personal problems."

Hearing the sound, Qin Shiming stared at Morton seriously, his eyes began to change, and he asked word by word: "What if we don't ask Chen Nan to apologize?"

Morton also immediately looked serious.

He continued: "We have to consider the issue of cooperation with you!"

Qin Shiming asked back: "Are you threatening us?"

Morton shook his head: "This is business, there is no threat!"

"If the conditions cannot be negotiated, special measures will naturally be taken."

Qin Shiming shouted angrily:

"Chen Nan is our Huaxia professor and our Chinese doctor!"

"Being in a foreign country, he represents us Chinese!"

"Mr. Morton, your Chinese is pretty good, but...you don't understand that there is an old saying in our Chinese nation, that's what it says."

"We share weal and woe!"

"I will be outside, and the military order will not be accepted!"

"Chen Nan, this is the medical general we have appointed to attend the meeting."

"He has the right to say what he says!"

"Similarly, we also have the responsibility to protect our professors!"

"As far as I know, Chen Nan didn't say anything wrong."

"This is just a normal communication and exchange."

"That won't work, isn't NMPA still letting us evaluate?"

While speaking, Qin Shiming's eyes became sharper.

Morton was unimpressed!

"hehe!"

"It seems that I have to apologize!"

"We may have to rethink our partnership."

"However, I have to persuade Mr. Qin."

"This matter is extraordinary!"

"Are you sure you don't want to consider it?"

"As long as you ask Professor Chen Nan to apologize, we can pretend it never happened!"

Qin Shiming slapped the table!

"Nonsense!"

"I, Qin Shiming, left my words here today."

"Chen Nan is the representative of our Chinese medicine, and he has the right to express his own academic opinions!"

"We'll protect that right too!"

"If you don't want to see this scene, you should discuss this issue with the organizer!"

"Instead of looking for me!"

"I, Qin Shiming, promise that Chen Nan is our Huaxia doctor, and we can't ask him to apologize to you for this!"

Morton took a deep breath, and his eyes became extremely sharp.

However, he still smiled: "I hope, Mr. Qin will not regret it!"

Qin Shiming got up straight away: "Go slowly, don't send me off!"

...

It's the end of the year, I went shopping today, I'm late, sorry!

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