I can extract side effects

Facing Williams' question, Tang Que was rare to remain silent.

As smart as him, he couldn't answer for a while.

After a while, he patted Williams on the shoulder and said with a complicated expression.

"Dawei, your question really stumps me, I'm afraid only Mr. Wei is qualified to answer you."

"However, this is indeed a very good question, and it is also a soul torture that every pharmaceutical company will face."

"After all, it often happens that pharmaceutical companies kill themselves. Some pharmaceutical companies' new drugs have completely cured a certain disease because of their excellent curative effect. Then, within a few years, the drug is still there, the patient is gone, the income is reduced, and the stock price It fell, and in the end the company disappeared.”

"I can only tell you from my own point of view, I very much hope that human beings can completely eliminate these diseases."

"But from the perspective of the company, from the perspective of the whole industry, the answer may be completely different."

His tone suddenly became serious, and he said, "As researchers, we should not waste our limited brain cells on such complicated problems."

"There is an old saying in Huaxia, but if you do good deeds, don't ask about your future."

"Today I give this sentence to you, work hard first, develop the drug, and talk about the rest later."

Williams pondered for a moment, nodded and said: "I understand, first develop the drug, at least we have the papers and bonuses. As for whether the company is still there, that is something the boss should consider, and it has nothing to do with us."

"That's...that's right." Tang Que paused, looked at him, and couldn't laugh or cry: "You are such a clever little ghost."

That's what he said, but after watching Williams go away, this question took root in his mind.

For a few days, as soon as he finished his work, he would ask himself silently in his heart.

"If a drug was developed to eliminate AIDS, would the company bring it to market?"

"Duanailing is already perfect. It has completely turned AIDS into a controllable chronic disease, and it can continuously grab money. It can be said to be an ideal drug in the eyes of pharmaceutical companies."

"Selling it for several years can bring billions of dollars in revenue to the company every year. Will the company be willing to give up such a flagship drug?"

"Perhaps, after the development of my own HIV gene medicine, the final outcome is just to be hidden in the snow, and it will be dusted in a certain cabinet. After waiting for several years, there may not be a chance to show up."

All kinds of questions lingered in his mind, and he seemed to have seen the future of the project in hand.

This kind of thing is not uncommon. After the drug is developed, whether it can enter the clinic or go to market depends on the decision of the company.

Although many drugs have good curative effects, their commercial value is not enough, and they will still be abandoned by pharmaceutical companies.

Large companies have many research and development projects in their hands, so they will naturally consider carefully the choice of drugs.

Generally, there are only small pharmaceutical companies with very few choices. When there is only one drug with excellent curative effect, even if it will be successful, it will not care about so many. It must be launched immediately to seize all the market. Even if the patient disappeared, at least enough money was made.

Just like the rise of the anti-drug giant Gilead, success and failure are hepatitis C.

This pharmaceutical company is not like Johnson \u0026 Johnson, Pfizer and other established pharmaceutical companies involved in a variety of disease fields like Octopus. It is very specific. Since its establishment, it has always focused on drugs for the treatment of two types of viruses.

One is AIDS and the other is liver disease.

Why these two fields? The reason is also very simple, because nearly one-third of HIV-infected people are also infected with hepatitis virus.

So Gilead is actually a wonderful drug in the field of anti-virus.

Just the two diseases of hepatitis and AIDS make it one of the top ten pharmaceutical giants in the world, with an annual revenue of more than 20 billion US dollars.

Gilead was also very down and out at the beginning. After the company was established, it has been a long time since it developed a drug that can be marketed.

Nine years later, the first drug was launched, and it took a full 14 years to turn losses into profits, and the first net profit finally appeared on the books.

Since then, the company has been on a rocket, and its performance has been blinding.

Although the successful development of a series of AIDS drugs made Gilead wear the halo of an anti-viral expert, but what really made the company famous and secured its status as a global anti-viral giant is the drug that cures hepatitis C .

After the anti-hepatitis C virus magic drug "Ji Dai" was launched, it directly raised the cure rate from 50% to an unprecedented level, approaching 100%.

Therefore, in the first year of its launch, it immediately swept the market and killed all the opponents of hepatitis C drugs.

It earned US$6 billion in two quarters, and sold US$10.3 billion that year, rushing to the second place on the world's best-selling drug list, creating a myth in the history of new drug sales.

Back then, the market demand in Eagle Country was extremely hot, with 140,000 patients taking the medicine.

There is no reason to make so much money. Gilead's drugs are very expensive.

The cost of a course of treatment for "Jidai" is 84,000 US dollars. Calculated, the average price of a pill exceeds 1,000 US dollars.

As for the other new drugs behind, they are more expensive, one hundred thousand dollars for a course of treatment.

In the following years, Gilead launched the "Genesis II", "Genesis III", and "Genesis IV" hepatitis C drugs, covering all 6 genotypes of hepatitis C virus, and they can quickly block the target virus, thereby eradicating hepatitis C .

Almost in just three or four years, hepatitis C was almost completely wiped out by Gilead.

Competitors are terrible. Johnson \u0026 Johnson, Merck and other giants have all announced their delisting of hepatitis C drugs.

However, within a few years, Gilead found that its hepatitis C drug performance began to decline rapidly.

The annual revenue dropped sharply from 30 billion to more than 20 billion, and the income of hepatitis C drugs was cut in half.

Back then, the entire global market for anti-HCV drugs shrank by half.

The reason is simple, the patients are cured, and the medicine can no longer be sold.

Hepatitis C is an infectious disease. When patients are cured on a large scale, there will be signs of rapid market decline.

The so-called flying birds are exhausted, and the good bow is hidden, that's it.

Even if Gilead tried its best, it could not save the company's decline.

The stock price has fallen all the way from $125, entered a long decline, and has fallen to the current $60, and is even slowly falling.

Follow the path of others, let others have no way to go, and in the end you will have no way to go.

It can be said that in terms of curing hepatitis C, Gilead perfectly performed this point.

However, when Gilead was developing hepatitis C drugs, it was still unknown. Facing a drug king product worth tens of billions of dollars, it undoubtedly did not think so much.

After the "Genesis Generation" sent it to the world's top ten pharmaceutical companies and brought huge money, they have obviously learned the lesson in this regard in terms of anti-AIDS drugs, and their pace has slowed down.

Although they continue to attack cities and land in other fields and develop new drugs for the treatment of hepatitis B, they basically no longer eliminate the disease completely, but take the route of allowing patients to take drugs for a long time.

When other pharmaceutical companies see Gilead's miserable situation in the field of hepatitis C drugs, they will naturally weigh it and make their own choices in the development of new drugs.

I believe it will be difficult for any pharmaceutical company to kill its own ace drug like Gilead.

Sanqing is also a mature pharmaceutical giant now, and it has finally gained a firm foothold in the anti-AIDS drug market. How could it dig its own grave so soon?

This is exactly what Tang Que is worried about. He is very worried that after the drug is developed, it will be stopped in the clinical stage.

As the person in charge of the project, he didn't think much about it at first, because the research and development of the gene drug was not going well, and he estimated that it would take at least two years to produce results. As for the launch, it would take three years.

Unexpectedly, now came a talented virus expert, who was too capable, and quickly broke through the bottleneck of the project, making the research and development progress a huge step forward.

According to this estimate, it may not take long for the new drug to be successfully developed.

So he had to plan ahead and figure this out first.

After much deliberation, Tang Que finally came to Wei Kang's office and knocked on the door.

As soon as he entered, Wei Kang said with a smile, "I was just about to call you over, and I have something to announce to you."

Only then did Tang Que notice that Chen Yiqing and Wen Renlong were still sitting in the office.

Chen Yiqing smiled lightly and nodded to him.

Wen Renlong winked at him and greeted him in a familiar way.

Tang Que put aside his thoughts for the time being, sat down, and planned to listen to what the boss had to say.

Wei Kang took out a document and handed it to Chen Yiqing who was facing him: "Old Chen, please see if you are satisfied with this document."

Chen Yiqing took it in doubt, and flipped through it.

Looking at it, he showed a shocked expression, and quickly grinned uncontrollably, with a strong joy in his smile.

After a while, he reluctantly put down the document, and asked as if he couldn't believe it: "Mr. Wei, is this true? The conditions are so good that it's unbelievable."

Wen Renlong saw that he was overjoyed and looked like he was hit by a pie falling from the sky, so he couldn't help shouting: "Old Chen, what a happy event, let's share it with my buddies."

Wei Kang opened his mouth slowly and explained: "This is a profit sharing agreement for the company. You all know that Lao Chen has paid a lot for the new drug Brain Nerve Regenerative Factor. Although this drug is very successful and sold well, but He's lost some credit as well."

Chen Yiqing interjected, "Actually, I don't mind this."

Wei Kang laughed: "As I said, there will be many honors and rewards that should be given to you. Now is the time to honor them. It's hard to say about honors. I'm still working hard, and I may not see them in the short term, but The reward is right in front of you."

He tapped the table with his fingers, and continued: "Everyone knows that most of the shares of Sanqing Group are in my hands. This is different from the shareholding structure of many technology companies."

"After a long time, there must be all kinds of rumors, saying that I took all the shares by myself, and the employees worked hard, but they were always part-time workers. They couldn't grow with the company, so they didn't have a sense of belonging."

"I can tell you very clearly that it is indeed the case. Sanqing Group will belong to me alone in the future, and it will not be listed, and there will be no chance of realizing it."

"I have my own reasons for doing this. Pharmaceutical companies are different from other companies. They not only want to develop new drugs, earn high profits, survive fierce competition, but also take on the social responsibility of curing diseases and saving lives."

"Therefore, Sanqing must not be coerced by any capital to do things that are only for profit and go against conscience."

"That's why I refuse to split shares."

"In fact, on the premise of not having shares, I am very generous in terms of giving money, which is obvious to all."

"Of course, this money may be enough for ordinary employees, but it is definitely not enough for executives."

"So, I drew up such a profit sharing agreement. How much money you can get in the future depends entirely on your own ability."

Wei Kang paused for a while, and seeing that the three of them were listening attentively, he continued.

"Among all the executives, you several laboratory directors are the company's most valuable asset and the most important asset."

"You three self-developed blockbuster new drugs, that is, drugs with an annual revenue of more than 1 billion US dollars, can get a dividend of one-thousandth of the company's annual net profit, based on the proportion of revenue."

"Take the brain nerve regeneration factor developed by Lao Chen as an example. Last year, the revenue was 3 billion U.S. dollars, accounting for about 5% of the company's total revenue. If the company's profit margin is 50%, then the profit allocated by this drug at 5% is 13.5% One-thousandth of a billion dollars is 1.35 million dollars, which is the dividend that Lao Chen deserves."

"If the annual revenue of this drug reaches 10 billion U.S. dollars in the future, and the company's profit margin is high enough, Lao Chen's dividend will definitely get higher and higher, and may even reach tens of millions of U.S. dollars."

"Of course, the dividends will not be paid until three years after joining the company, and you will lose your qualifications after leaving the company. It can be regarded as the benefit of growing together with the company."

"Although this money cannot make you rich like stocks, it is still a considerable income."

"After a long time, I believe that your social status will not be worse than that of Internet upstarts."

As soon as the words fell, Wen Renlong exclaimed: "Fuck, Lao Chen has become a multi-millionaire without knowing it. It really can't be justified if we don't invite us to the big sword."

The smile on Chen Yiqing's face froze for an instant, and he waved his hands and said, "As long as Mr. Wei is willing to go, even if I am scolded by my wife, I have to go all out and invite you all."

"This..." Wen Renlong resentfully said: "Even if you escaped a catastrophe, I ask for a lower level. Please go to the island yacht to climb the head office."

Chen Yiqing smiled slightly and said: "In this case, why not leave it to me. By the way, your Duan Ai Ling is also selling very well, and it will definitely become a billion-dollar drug. By then, your dividend will not be as high as mine. few."

Wen Renlong said triumphantly: "Of course, I am not a fuel-efficient lamp."

There was a smile on his face, and he was already thinking about how to spend the huge sum of money. He could buy such a flamboyant sports car as Lamborghini and Ferrari.

Although his annual salary is one million, Aaron usually spends a lot of money. It is still a bit difficult to spend a lot of money to buy a supercar.

Now I suddenly have a huge dividend income every year, and the income has skyrocketed in an instant, and I can afford some things that I usually covet.

"Sure enough, the ancients never deceived me. Horses don't have night grass and don't get fat, and people don't have windfalls and don't get rich!" Wen Renlong thought about the happy life of buying, buying, and buying in his mind, and couldn't help but feel a lot of emotion.

He reached out and patted Tang Que, and blinked triumphantly: "Brother Que, you have so many genetic medicines, the dividends must be very fat. None of the three of us lost this time, and all of them made a fortune."

"It's a good thing there is a broken love spirit, otherwise I will be compared this time. Hahaha."

Looking at Wen Renlong's excited look, Tang Que couldn't help but twitch his eyes.

He knew that several of his genetic medicines were selling well and would definitely break the $1 billion mark, especially the thalassemia genetic medicine, which was simply a cash cow.

But this is not the focus of his attention, "Aaron is so happy, that's right, Duan Ailing is his biggest achievement in the company, it must be very important to him, whether it is in terms of performance or money .”

"Aaron will definitely be unhappy if he hears that AIDS can be completely eradicated and Duan Ailing can't be sold for a few years."

"It can't be that he is so excited, but I ran out to pour cold water on him and told him that you can receive dividends this year, but you won't be able to receive dividends next year."

Tang Que thought in his heart: "Forget it, this happy day will not be a disappointment."

"When the HIV gene drug is almost developed, I will ask Mr. Wei this question."

"Anyway, no matter whether it is listed or not, there should be a result by then."

Thinking so, he looked at Wen Renlong and squeezed out an encouraging smile.

"Aaron, come on, you are the best, I believe you will develop the next billion dollar molecule soon."

Wen Renlong suddenly had a chill: "Old Tang, don't be so gross, I have goosebumps."