I can extract side effects

Kunming, Infectious Disease Hospital.

In the treatment room, a middle-aged man in his forties sat nervously on a chair with an uneasy expression.

No wonder he was so nervous, it was because the situation at the scene was a bit scary.

Around him, there were a dozen or so doctors in white coats.

They all stared at him with scorching eyes, looking up and down, like a ghost seeing a roast chicken, or a satyr seeing a beautiful woman, the eyes were so hot that it was a little frightening.

After a while, the man was stared a little hairy, and he looked timidly at the doctor in front of him.

"Director Fu, didn't you ask me to be a volunteer for Sanqing's new drug clinical trial? What about the medicine?"

Director Fu is in his fifties, his hair is a little gray, he looks kind and amiable, and he said with a smile: "Come on, we are waiting for someone, please be patient."

The man's face suddenly changed, and he said with a mournful face: "I'm not Fuyang, am I? Or have some other terminal illness? You can't hide it from me."

"Don't think too much, it's nothing, your illness is recovering." Director Fu said a few words of comfort.

"But you guys look at me, don't you think it's a good thing?" The man looked like he was about to cry.

"Hehe, it's like this..." Director Fu was about to speak when suddenly footsteps came from far away.

He suddenly smiled: "It seems that the medicine and people have already arrived."

After speaking, he turned and faced the door.

Soon, Director Fu led a group of people to the patient. There were five or six people in this group, and they were all wearing white coats.

A square-faced, dignified middle-aged man glanced at him and asked, "Is this drug tester No. 0?"

Director Fu nodded and began to introduce the man's profile.

"Director Han, Patient 0 is 46 years old and has been suffering from AIDS for more than ten years. He has taken almost all anti-AIDS drugs on the market, and many of them are already resistant."

"He is currently taking Duanailing, and the HIV virus in his body has not been detected. However, after genetic analysis of some lymphoid, blood and other tissue cells, it was found that there are a large number of HIV virus gene pools remaining, which is a very suitable clinical test subject."

Director Han nodded, smiled at the patient, stopped talking, and stood aside to watch.

Director Fu stretched out his hand to another burly man, and said with a smile on his face, "You are Tang Que from Sanqing Group, I have admired you for a long time."

He looked at the small box in Tang Que's hand, and asked curiously, "Is this the gene therapy drug you developed?"

The patient looked at Tang Que's protruding biceps under his white coat, his face was full of surprise, and he thought: "This big guy is actually a scientific researcher? I really can't tell. If it weren't for this white coat, I would have thought it was Where did the fitness trainer come from?"

Tang Que smiled and nodded, and handed over the small box in his hand: "This time the medicine is a bit special, it is not an inactivated biological preparation, and it must be kept in cold storage. I just want to see the effect on the patient with my own eyes, so I went with Director Han. coming."

Director Fu took it carefully, and felt a chill when he touched it. He put it on the table, opened it gently, and there were ten tubes of injection lying quietly inside.

Everyone took a step forward in unison in an instant, and looked over greedily, showing an expression of great anticipation.

This is the world's first HIV gene medicine!

Director Fu picked up a tube of injection, looked at the liquid inside, his eyes became a little fascinated, and said excitedly: "Next is the moment to witness history!"

Director Han stared at the genetic medicine without blinking, showing a hint of longing.

The patient also looked excited at the moment. Although he didn't understand much, he felt that everything seemed very powerful.

The injections that need to be refrigerated, transported and stored are placed in such a high-end box, and the whole looks very high-tech, just like a Hollywood science fiction blockbuster.

He had never seen such a big scene before, and couldn't help but gear up, a little eager to try.

"Let's start." The patient couldn't help urging.

"Hehe, why are you so impatient." Director Fu said with a smile, walking to him.

Disinfecting and pricking the needle, a set of movements is smooth and smooth, and the liquid in the needle tube is quickly injected into the patient's vein.

The whole process took less than half a minute to complete the treatment.

The patient pressed the cotton ball with his fingers, and was still a little dazed: "What? This is the end of the matter? I thought there were so many people, it would take a few hours anyway."

Director Fu shook his head: "What are you thinking, it's like a vaccine, it's a one-shot thing."

He looked at the patient, his eyes became sharper: "However, follow-up observation is the most important thing."

"You have to stay in the hospital for two weeks this time without taking medicine, but you have to provide some blood samples and tissue cells every day, and we will conduct tests."

"I don't need to take medicine after leaving the hospital, but remember to come and check every week."

The patient opened his mouth wide, not daring to say anything: "I don't need to take medicine after I leave the hospital? You know I have AIDS, what should I do if I relapse?"

"Hehe, it is to test how long you can stop taking the medicine and keep the HIV virus clear, so you can't take medicine."

Tang Que interrupted suddenly: "So after you leave the hospital, you'd better be more conscious, keep in touch with the CDC, and at the same time, be careful in your daily life."

The patient opened his mouth and wanted to refuse, but after thinking about the benefits of trying the medicine, he endured it and said angrily, "Okay, I understand."

Director Fu comforted: "It's also for your own good. This gene drug, just one injection, can completely cure your AIDS and prevent future troubles. If the test goes well, you won't need to take medicine anymore."

When he said this, the patient cheered up: "Haha, really? That's great, I can finally get rid of the damn thing of AIDS."

"Okay, I'll give you another check, and then you can go to the ward with the nurse."

Director Fu personally performed a physical examination on the patient, and exhorted with satisfaction.

A group of people walked out in a mighty manner and came to a meeting room.

Director Han couldn't wait to ask: "How is it? Are you sure?"

"It seems that everything is going well so far. After the patient was injected with the drug, his body temperature rose a bit, but nothing else was abnormal. We will know what's going on after the blood sample is checked tomorrow." Director Fu pondered.

"There will be a few more patients coming tomorrow and the day after tomorrow, and there will be more cases. We will record all the reactions of the patients in detail."

Tang Que agreed: "Although the cell experiment and animal experiment are very successful, this is the first time it is used on a patient. You must proceed with caution. If you have any adverse reactions, you must notify us in time."

Director Han said expectantly: "Great, then I'll wait for your good news."

He looked at Tang Que: "Director Tang, I have something to discuss with President Wei, let's go back together."

The last time Wei Kang told him that the HIV gene drug was successfully developed and that the HIV elimination plan could be upgraded to 2.0, he was so excited that he rushed over immediately and wanted to meet Wei Kang in person to discuss this matter.

We just met, and before we had time to talk, we learned that the gene medicine was going to be tested here, so we immediately came over with Tang Que to check it out for ourselves.

Sure enough, he was not disappointed. After seeing the genetic drug with his own eyes, he was overwhelmed by this seemingly very technical drug.

As expected of a gene drug developed by Sanqing Group, it is very high-end just because of its appearance.

With this thought in his mind, he became more eager for version 2.0 of the HIV Elimination Plan.

Version 1.0 has been implemented very smoothly and has been a great success.

Everything went as planned, and the chain of transmission of the HIV virus was completely cut off.

The increment is completely gone.

However, how to deal with these existing patients in the future made him a little embarrassed.

Although they can continue to take medicine, the problem is that this is not something that will be settled in a short time.

These people have to take medicine until they are old, and it will take decades, which is undoubtedly a huge burden on the medical system.

Although it can be converted to medical insurance in a few years, so that patients can bear part of it themselves, but the free drug delivery is used to it, and it will inevitably not arouse the opposition of patients.

And if the drug is taken for a long time, what should I do if drug resistance occurs?

What if the patient has some underlying disease?

Or what if the patient cannot take the medicine continuously for some reason?

There are always all kinds of accidents in life. If a patient misses taking the medicine for a period of time, it is easy to get back positive. What if he infects others again?

In short, it is impossible to persist in eating for decades without making any mistakes.

He is having a headache for the follow-up measures.

Unexpectedly, joy fell from the sky.

Sanqing has successfully developed a gene drug that can be completely cured, which can completely kill these existing viruses.

Why didn't this make him both surprised and happy, and called out to God to help me.

So after hearing the news, he rushed over immediately to discuss the specific implementation plan with Wei Kang.

He has also seen the HIV gene drug with his own eyes, and he is very relieved, and the patient seems to be in good condition after injection.

All this gave him confidence in the plan.

Taking advantage of the few months of clinical trials, we can just make preparations in advance.

After returning to Sanqing headquarters, he quickly met Wei Kang.

The two sides exchanged greetings and sat down.

Director Han was full of enthusiasm and was full of praise for gene medicine.

"Mr. Wei, today is really eye-opening. I saw the legendary HIV gene drug. It is very high-end at first glance! Sanqing has become the world's first pharmaceutical company that can cure AIDS. It is really amazing."

Wei Kang smiled slightly: "Director Han is polite, this is the result of the R\u0026D personnel."

"It's still too early to see the clinical results."

"Mr. Wei is so humble. I saw that the patient was fine after the injection of the drug. When we left, he was in good spirits and only had a little fever." Director Han couldn't help giving a thumbs up.

"However, this drug uses a recombinant virus vector, so there will be some difficulties in transportation and storage?" Director Han asked.

Wei Kang nodded: "Yes, this may not be very friendly to economically underdeveloped regions. Since it is a live virus carrier, it needs long-distance cold chain transportation, otherwise there is a risk of failure."

"Due to the particularity of the recombinant gene virus, large-scale production is also a bit difficult. It is not possible to use chicken embryo cell culture virus, that is, eggs, which are commonly used in vaccines, for mass production. It is necessary to use a cell cultured and isolated from rhesus monkey lymphoid and visceral tissues. , can continue to reproduce in large numbers, I am afraid it will be difficult to popularize in a short period of time.”

"Here," Director Han suddenly panicked, patted his chest and said, "Don't worry, if you have any difficulties in production, just mention it, and I will coordinate and solve it."

Wei Kang pondered: "We only produced gene medicines for rare diseases in the past. The quantity is relatively small, and it is not a live virus carrier, so there is no problem. But we have to face millions of AIDS patients in China, and even tens of millions of patients abroad. Our Sanqing family may not be able to afford this production capacity.”

"What's more, there is the problem of long-distance cold chain transportation, especially cross-border cold chain transportation, which directly doubles the trouble."

"So, I want to authorize this drug and let capable pharmaceutical companies produce it by themselves, so as to solve the problems of remote origin and insufficient production capacity."

Director Han's eyes lit up: "This is indeed a very good solution."

"So, I may hold another press conference to meet with old acquaintances from multinational pharmaceutical companies." Wei Kang said with a chuckle.

Director Han smiled meaningfully: "It should be. The whole world is trying to solve the century-old problem of AIDS. Since Sanqing is at the forefront, it is natural to take responsibility for all mankind and unite the entire pharmaceutical industry to solve it together. this problem."

Wei Kang also smiled: "Governments of all countries are also duty-bound. In this regard, as a pioneer, China must not mind playing an important role and becoming the leader of the world."

The two looked at each other and smiled, all the tacit understanding was in silence.

"Okay, let's talk about the price." Wei Kang coughed lightly and turned to another topic.

"It's still the same, the domestic price will be very favorable, and I will do charity to repay the society, and the main profit will come from overseas income. I know that these rich countries have announced a series of plans to end AIDS. Their wallets are full and they are holding money to buy. Since So, I’m not being polite anymore.”

"Mr. Wei, don't worry, this aspect will never let you suffer too much."

Director Han looked serious, and said, "I heard the news that you are on the list of this year's Huaxia Public Welfare Charity Award. This is an affirmation of Sanqing's long-term contribution to the society and its courage to shoulder social responsibilities."

"Haha, it seems that I will continue to struggle and show greater responsibility." Wei Kang laughed.

The following negotiations went smoothly, and the two reached a general agreement.

Director Han returned satisfied, and now he is waiting for the results of the clinical trial.

As long as the HIV virus in the body does not recur within a few months after the AIDS patient stops taking the drug, the HIV Elimination Plan 2.0 will be stable.

*****

Two weeks later, Director Fu was completely shocked when he saw the test results in front of him.

"The patient will show mild cold symptoms at the beginning, low-grade fever, runny nose, nasal congestion, general fatigue, etc."

"These symptoms lasted for four to five days, and genetic analysis of samples taken from the patients during this period revealed that the HIV virus gene fragments were rapidly reduced in the tissue cells."

"One week later, the HIV gene fragments could no longer be detected in the patient's tissue cells. At the same time, the patient's cold symptoms began to heal on their own. Three days later, the symptoms disappeared and the patient completely recovered."

"Two weeks after stopping the drug, the HIV virus in the body has disappeared, and the patient can be discharged from the hospital. The follow-up situation needs to be observed again."

"It's amazing to have such an effect with just one injection."

Director Fu closed the report and sighed: "Sanqing has developed an amazing drug."

"With this kind of genetic medicine, there will be no more AIDS in China."

"What a great achievement, what a great company."

He quickly sent the latest news to Sanqing and the CDC.

One month later, the four test results of the patients participating in the clinic after stopping the drug all showed no signs of active replication of the HIV virus.

Although the time is short, doctors are more likely to have a long-term remission of their AIDS.

Whether it is cured or not, it will take a long period of observation before a final conclusion can be made.

But it is clear that the dawn of healing is as unstoppable as the morning sun, and sooner or later it will shine on the whole world.

After receiving the results of the clinical trial, Sanqing held a formal press conference to announce the successful cure of AIDS.