I can extract side effects

"Over the years, we've tried to clear up bacterial infections with various antibiotics, sometimes with less success."

"But if you use the laws of nature and use the bacteria's natural enemies to attack them, sometimes things can take unexpected turns."

Williams is bright-eyed and eloquent.

Everyone listened attentively and held their breath.

"All things generate and restrain each other, and highly poisonous things are often accompanied by natural enemies."

"Bacteria have survived on the earth for billions of years, constantly evolving and becoming more and more cunning. Humans can no longer defeat them by relying on antibiotics alone."

"We need allies, and they must be very powerful helpers. Fortunately, there is something in the world that has also survived for billions of years. They know how to deal with bacteria and are natural enemies of bacteria. This is bacteriophage, a specialized Viruses that infect and destroy bacteria."

"Just like humans, bacteria can be infected with viruses and die. A phage is much smaller than a bacterium. It attaches to the bacterium, injects its own DNA, and then reproduces in the bacterium until the bacterium bursts and dies."

"Antibiotics are the chemical arsenals made by bacteria, which have strong lethality against other bacteria, but antibiotics have a disadvantage, that is, they cannot mutate and cannot keep up with the pace of bacterial evolution. When bacteria become resistant to drugs, they are completely useless. "

"But phages are different. They can mutate. When the bacteria change, the phages will also change and multiply and grow in the newly formed bacteria. This mutated phage has an advantage and begins to multiply and become a dominant group."

"Bacteria mutated again, and phages mutated immediately. The two sides continued to evolve, like a life-and-death arms race."

"If we can get them to fight for humans, even if the bacteria mutate, they will keep fighting."

"Isn't it a wonderful thing to use viruses to eliminate drug-resistant bacteria?"

"Next, let me talk about my thinking. Each bacterium has dozens of hundreds of corresponding phages. We collect drug-resistant bacteria from patients and then screen out the phages that can eliminate it."

"In the next step, we use gene editing technology to optimize the phages to enhance their ability to lyse bacteria so that they can exhibit the most effective therapeutic effect."

"Of course, this screening and optimization stage will take a certain amount of time, but we have AICell, which can be transformed with the help of machine learning, and I believe the speed will be much faster."

"At present, there are related papers that prove the broad prospects of phage therapy in the treatment of multi-drug resistant infections. This may be a development direction of biomedical technology in the future, and we should not miss it."

"That's about it."

Williams ended his presentation with a smile.

"Papa papa!" Tang Que clapped vigorously: "A very ambitious project, the research on bacterial resistance is a direction with great potential, very exciting."

After a burst of warm applause, he looked around again.

"Okay, if any of you have any wonderful ideas, you can discuss them together and brainstorm together, maybe it can really be done."

Everyone looked at each other in blank dismay, and fell silent one by one.

A timid voice suddenly sounded.

"Well, I have an idea."

Everyone looked over together, and a thin and small man stood up nervously.

Tang Que nodded approvingly: "Huang Qin, you are very good. I am very relieved to see you grow from a rookie to a veteran now."

He asked kindly: "What do you think? Let's hear it."

Huang Qin swallowed, and said loudly, pretending to be calm: "Hello everyone, you all know that I was transferred to the animal protection department recently, and I am not considered a biological laboratory person, but I am from here. Those who go out have always regarded this place as their home and treated everyone as brothers."

"So now I have a few potential projects in my hands, and I immediately thought of coming to discuss with my brothers. Hehe." He smiled honestly, and quickly started to introduce.

"It's like this. Before we cooperated with Syngenta to edit gene crops, the effect was very good. They all enjoyed the sweetness. After the news got out, many companies came to our door, wanting to cooperate with us to develop new gene editing. plant."

"We have cooperated with the Xinjiang Academy of Agricultural Sciences to develop a super long-staple cotton. We want to beat Egyptian cotton and kick horse cotton, and become the brightest pearl in the world's cotton industry."

Just like every scientific researcher, Huang Qin became more and more excited when he talked about his field of expertise.

The apprehension and tension in his heart had long since dissipated, and he danced and talked non-stop.

"You may not know much about cotton. The best cotton in the world is Egyptian cotton, which is very expensive. Although our Xinjiang cotton is very good, there is still a big gap."

"The longer the fiber of cotton, the better. The quality of long-staple cotton is the best, but the fiber will become thinner when it grows, resulting in low strength. Egyptian cotton is unique in this respect. Not only the fiber is very long and thin, but also its strength is also low. It is very high, so it can stand at the top of the pyramid."

"If you rely on purely natural means, it may be difficult to catch up, but with gene editing technology, everything will be different."

"We have already sequenced the Egyptian cotton gene with the Academy of Agricultural Sciences. As long as the genes that control the strength and fiber length are edited, I believe that long-staple cotton that is better than Egyptian cotton will soon be obtained. Let the world know that only we Xinjiang cotton is the supreme king of cotton in the world."

"This is the first project I want to talk about. The second project is similar to this one, but it is about animals. This is gene-edited goats. Everyone should have heard of the EEDS of the Inner Mongolia wool industry. 70% of the world's wool Cashmere is supplied by it, which is very important.”

"Cashmere is a top-grade thermal insulation material taken from goats. It is so soft that you won't feel uncomfortable even if you wear it next to your body, and its thermal insulation ability is even more outstanding."

Huang Qin suddenly stretched out his hand, touched Tang Que's sweater next to him, and said, "Look, everyone, the sweater on Director Tang's body is made of cashmere. It's very thin and warm. You can come up and feel the feel."

He glanced out of the corner of his eye and saw Tang Que staring at him, and immediately shrank his neck: "Of course, if Director Tang agrees."

Tang Que stared at him with knife-like eyes, he laughed and said nothing.

Everyone urged them wisely: "Hurry up and talk, don't talk about it."

Huang Qin cleared his throat and said, "Although the cashmere production of EEDS accounts for the majority of the world, the top cashmere is still in the hands of foreigners. We can't overcome this for the time being, but also, with gene editing technology, we can We can also work hard to catch up in this regard.”

"Editing the genes of goats to produce top-quality cashmere is our goal, and the project is progressing well."

"The third project is also a gene-edited animal, a kind of gene-edited cow. We want it to have the texture of top-quality calfskin, because domestic cowhide is relatively rough and the quality is not good. Of course, our tanning technology is also average. But now you can overtake on detours, and if tanning is not enough, you can rely on high-quality cowhide.”

"Our goal is to let the leather of domestic bags beat Hermès, and make the leather of counterfeit bags better than the original Hermès."

"the fourth……"

"These are the projects I'm working on now. They sound very attractive. They are currently very short of people. Everyone is welcome to actively participate."

After Huang Qin finished the big call, he looked at everyone expectantly.

"Crack!" Tang Que took the lead in applauding, and praised: "They all look great and have great potential. As long as they are developed, they are all big projects that will change the world."

Encouraged by Tang Que, someone immediately raised their hands.

"Brother Huang, I'm very interested in that cotton project, please take me with you."

"The cashmere project is also very interesting. It will be very meaningful if the production of cashmere can be increased and popularized to the public."

"I want to participate in the calfskin project. My wife loves to buy big-name bags. They say that the leather is good, and domestic brands use imported leather. Brothers, this is the IQ tax paid to women. Can you buy these luxury goods? Playing all the big cards, I really wish for it.”

There was a lot of discussion, and many people expressed interest in these projects.

Huang Qin was overjoyed immediately, smiling from ear to ear.

He knew that if he wanted to attract people, the leader had to nod his head. As long as Director Tang expressed his opinion on the spot, these people would definitely be willing to go.

"Today's brainstorming was very good, and everyone's performance was very good, which really impressed me."

Tang Que showed a satisfied smile, waved his hand, and motioned for the meeting to continue.

*****

Williams drove to the Kunming Sewage Treatment Plant in the outer suburbs.

A staff member greeted them, and after the two put on protective clothing, they walked towards the sewage pool.

In the distance, several huge pools came into view, and a stench hit the nostrils instantly.

Standing outside the fence around the pool, Williams watched the water rushing under his feet. The water was dark brown and looked filthy, with a thick layer of scale-like yellow foam floating on it.

The pool dam is full of sludge, and some disgusting algae can be vaguely seen.

Fine rubbish such as toothbrushes and bottle caps swirled in the pool water, bobbing up and down.

The staff asked with a smile, holding a transparent plastic bucket in his left hand and a long water collector in his right hand.

"This is the sewage sampling point. Is it enough to scoop up a bucket of sewage here?"

Williams nodded, watching the other party quickly scoop up the water spoon by spoon and pour it into a transparent plastic bucket.

The water in the bucket was cloudy, but it was cleaner than the sewage pool we just walked through. At least there was no garbage or yellow foam in it.

A few days ago, he contacted the sewage treatment plant through the company and asked to come to take samples.

Sanqing Group is a pillar industry in Kunming City and has a great reputation. It has always been unimpeded in doing everything.

This time was no exception. When the sewage treatment plant heard that it was Sanqing's scientific research activity, it immediately agreed and sent a staff member to cooperate with him.

Williams put on gloves, took the transparent plastic bucket, looked at the sewage in the bucket intently, and smiled with satisfaction.

"Thank you, these are enough."

Seeing the completion of the task, the staff felt a lot more relaxed, and asked curiously.

"Aren't you Sanqing a pharmaceutical company? Why do you come here to collect sewage? What is it for?"

Williams shook the bucket in his hand and said with a chuckle, "You don't know that. Take a closer look at the bucket of water and tell me, what do you see?"

The staff member scratched his head in confusion: "Except for some sand floating in the water, I can't see anything."

"Hehe," Williams said meaningfully, shaking his fingers, "Although we can't see it, there is a war going on inside."

"Ah?" The staff was stunned: "What war? I don't understand."

"As we speak, there are billions of bacteria out there fighting to survive because there are tens of billions of phages, waging a bacterial war to eat them all up."

After Williams explained, he didn't say much, just smiled, and walked back with the bucket.

The staff gave a half-understanding "Oh" and followed closely.

Soon after returning to the company's laboratory, Williams put on a white coat and rubber gloves, and carefully used a pipette to put the sewage into the prepared test tubes.

Raw sewage is a perfect breeding ground for bacteria, and it's also the best place to get bacteriophages.

Williams collected the sewage and brought it back to the lab just to start his new project on phage therapy.

He injected sewage into specific culture bacteria. There are hundreds of phages in the sewage. Some phages will attack this specific bacteria, attach to it, multiply and sterilize.

And that's exactly what he wanted.

Of course, in some special cases, some bacteria will only have a few phages that are effective against them.

After that, he can select the most aggressive ones from these phages and cultivate them.

Finally, try gene editing it to see if it can be further optimized.

This is the ideal state in Williams' mind.

Once he has a certain research foundation, he can consider collecting drug-resistant bacteria from patients and officially start clinical research.

However, when he put the petri dish under the electron microscope to observe.

He saw an unexpected picture.

In addition to bacteria and phages, there is another group of uninvited guests.

Some microplastic particles, like dust floating in the air, condense together, like water mist, all over the petri dish.

"Hell, there are too many of these plastic particles, and they burst my bacteria."

Williams was furious, staring at the microscope, wishing the phages were eating plastic particles instead of bacteria.

"Damn it, is the plastic crisis this bad? Even city sewage is everywhere."

"It seems that we must find a way to remove the plastic particles, or look for phages in another place."

Disappointed in his heart, he got up and walked out the door.

For days, he pondered possible solutions.

The petri dish was left on the test bench by him and completely forgotten.

Until a week later, Williams finally thought of a way.

Then he ran over excitedly.

"Huh? These petri dishes seem a little different."

I put the glass dish under the light and observed it, and found that the liquid was not so cloudy.

Suddenly curious, put it under the microscope again.

"My God! What did I see?" Seeing the picture under the camera, Williams was shocked and exclaimed.

"Most of the microplastic particles have disappeared, and there are only some leftovers. What's going on?"

He frowned, thinking hard, for a while, a flash of inspiration suddenly appeared in his mind.

"Could it be decomposed by the bacteria inside?"

"Oh my god, I found a bacteria that can decompose microplastic particles!"

Williams muttered to himself, his voice trembling, and his breathing suddenly became heavy.