I can extract side effects

Department of Nephrology, West China Hospital, Chengdu, Sichuan Province.

Dr. Tang picked up the water glass on the table and took a big gulp. The ice-cold tea entered his mouth, making his chaotic mind instantly feel clear.

He looked up at the clock on the wall, and found that more than two hours had passed since he sat down.

"There are still two hours to get off work." He muttered something, and he pressed the call button on the table, quietly waiting for the arrival of the next patient.

With the sound of mechanical electronic calls, the door was pushed open, and a middle-aged woman walked in with a timid girl.

"Please sit down, what's wrong?"

While speaking, Dr. Tang took a glance, and saw that the middle-aged woman had rough skin and simple clothes. The girl should be her daughter. Although she was young, she had a haggard face and dull eyes, so she was definitely a patient.

After the girl sat down, the middle-aged woman immediately handed over a test report with a flattering smile on her face.

"Doctor, look at my daughter, she is young, she has not had a good appetite, and she is not feeling well. The father of the child always said that she is fine and thinks she is hypocritical, but I am always worried, so I took the child all the way to the provincial capital to see a doctor. Well, it shouldn't be a big problem."

Doctor Tang showed a kind smile, and looked at the test sheet with ease.

"Let me take a look at the test sheet first, you did it this morning—huh?"

His voice suddenly rose, and he sat up straight, staring at the test sheet without saying a word.

After a while, a solemn look appeared on his face, and his eyes became stern.

"The creatinine is more than 700, and the normal value should not exceed 114umol/L. The girl is thin and thin, and most of them are around 70-80. Your kidney failure is already very serious, and it may be uremia."

"There is also a B-ultrasound that shows that the kidneys have shrunk to a certain extent, and the glomeruli have sclerosis..." As he spoke, he glanced at the 18-year-old patient and couldn't help shaking his head.

The middle-aged woman was stupefied with fright: "Doctor, this, this, I don't know, the child has always been fine."

As soon as she hugged her daughter, tears burst out of her eyes: "My life is so miserable, woo woo woo, how did you get uremia~"

Doctor Tang sighed, and comforted him: "In short, kidney failure is impossible. I hope it's not the advanced stage of uremia. Anyway, we must find out the cause first, and then do dialysis early."

"Dialysis?" The middle-aged woman suddenly burst into tears: "If it is uremia, how long can the child live?"

"Don't cry first!" Doctor Tang said solemnly: "This disease is usually caused by the elderly in their fifties and sixties. It is rare for young people, let alone 18-year-old patients. There must be a special reason. Think back Let’s talk about the development of this disease from beginning to end.”

The middle-aged woman wiped away her tears and fell into memories.

Dr. Tang concentrated his attention and began a round of investigation-like interrogation to find the original disease.

Fortunately, this parent really loves his daughter, and he remembers many details very clearly. Once he asked about it, he could easily find out the real culprit.

It turned out that after the little girl had menstruation at the age of 12, she felt so painful every time she had menstruation. Her mother took her daughter to a doctor in the village and said that the dysmenorrhea was caused by poor Qi and blood. secret recipe.

This secret recipe is said to be specially formulated to regulate the body and replenish qi and blood. As long as you drink it for a long time, you will naturally stop dysmenorrhea after conditioning.

The mother is like a treasure, and since her daughter was 12 years old, she has been drinking two bowls of secret soup every day, until a month ago, for 6 years, every day.

"Then show me the prescription." Doctor Tang frowned.

The middle-aged woman shook her head: "There is no prescription, I go to get the medicine regularly."

"Uh," Dr. Tang couldn't help but choked on his forehead, speechless for a while.

He suddenly felt angry: "Just such a bowl of herbal decoction with unknown ingredients and unknown efficacy, you let your daughter drink it every day, every month, and drink it for 6 years without going to see a doctor." ?”

"As a result, I have kidney failure after drinking it???"

The middle-aged woman suddenly burst into tears: "I can't help it. My family is too poor in the countryside. I haven't been with my daughter since I was a child. I only started to take care of my daughter when I was old. I don't understand anything, and I don't have money to see a doctor."

"The child's father also said it's okay, and blamed me for messing around. I finally asked my relatives to scrape together 3,000 yuan before I came to the big hospital for treatment. Huh, huh!"

"Doctor, isn't this dialysis expensive? I only have 2,000 yuan on me now, and I have to leave 300 yuan for travel expenses. Do you think it's enough?"

"Oh~" Doctor Tang sighed, not knowing what to say.

He also knows that it is not easy for rural women to raise their daughters because they don't understand anything and work outside all the year round.

After all, this mother cared about her daughter, knowing that her daughter was not feeling well, she would find a way, and it took a lot of effort to cook the soup every day.

It is foolish to take my daughter to eat the secret recipe, but how can I bear to be harsh?

Dr. Tang had never heard of the rural area where they lived, so it can be seen that it is remote. Apart from the township health center, the only place to go to the so-called miracle doctor is to see a doctor there.

At least this mother will care about her daughter's dysmenorrhea and her daughter's inability to eat, and will run around to raise money. Even if she quarrels with her family, she will take her to a big hospital for treatment.

Compared with many who are indifferent to their children, they are already very caring parents.

As for the child's father, he is also ignorant, but he really can't scold him.

Counting the old man, a family of five or six people, farming in the ravine, and the whole family relying on him to eat alone, life is bound to be rough.

In his world, feeding the whole family, I am afraid that all the energy has been exhausted.

After thinking about it, I don't know who to blame for this girl's tragic life.

If the girl was really diagnosed with uremia, the family would not be able to spend much money at all. Even the 3,000 yuan for this doctor's visit was borrowed, which may not even be enough for intubation and ostomy.

Even raising money can make her dialysis 10 times? 20 times?

You must know that a uremic patient needs dialysis two or three times a week, and has been on dialysis for more than ten years. How can there be so much charity to keep her doing it.

As for the kidney transplant, it can only depend on the arrangement of fate.

Dr. Tang felt a sense of powerlessness in his heart. Even though he had practiced medicine for many years, he still felt very sad to see such a young flower being folded off by someone and shrinking in front of him.

In particular, no one can blame such a situation, because it is not easy for anyone.

This is the case in the real world. If someone is victimized, there may not necessarily be a corresponding perpetrator.

I can only blame the world for being too impermanent and life suffering too much.

Doctor Tang sighed again. In just half an hour, he had already sighed more than in a whole year.

"Uremia is generally called the silent killer, because it develops slowly from early kidney disease. Over a long period of time, the body adapts slowly, and there is no obvious manifestation at all."

"Only when the toxin accumulates to a certain level will it lead to loss of appetite, just like the whole body organs are soaked in toxin, and the gastrointestinal tract is the same, so the appetite will be lost."

"Well, I'll make an order for you first to have a puncture, and then hospitalized for treatment. I hope it's early, so you can still be saved."

The middle-aged woman cried and cried, repeating the same sentence over and over again. The family is poor and has no money for dialysis. Even if she is diagnosed, she can only be discharged from the hospital with tears in her eyes.

The daughter sat aside, her expression was numb all the time, she didn't say a word, there was no trace of agility at this age in her dark eyes, as if her strength had been drained by illness long ago.

"Hey, how about this. I'll give you a chance to try a drug in the clinic," Dr. Tang said with some distress, but also with a big head: "Sanqing Group has a new drug for the treatment of chronic kidney disease, which has just entered the third phase of clinical trials."

"Uremia is actually the end-stage of renal failure. If your daughter's data is not particularly bad, she will probably be in the fourth or fifth stage. She is still young, her body is more resilient than the old men, and she has no messy underlying diseases. Good test subjects."

"This medicine is mainly to increase the filtration capacity of the glomerulus, which is helpful to the recovery of kidney function. Sanqing's medicine is generally relatively safe, and there will be no messy side effects."

"The most important thing is that it returns the money. For the first phase of the experiment, you can get at least several thousand fees. You can use this money to give your daughter dialysis. Free food and lodging during the experiment. In short, it can alleviate some of your difficulties."

"Do you agree?"

"Great! I agree." The middle-aged woman nodded repeatedly, and a smile bloomed on her tear-stained face.

"Okay, after you finish the puncture, come over and ask me to sign the consent form."

Doctor Tang sent the patient away, couldn't help sighing again, and continued to call the next one.

The next patient was a boy who had just entered high school. Because of oliguria and foamy urine, he suspected proteinuria and came to see a doctor.

The examination results showed a slight increase in creatinine, more than half of the glomerular sclerosis was found in the renal puncture, and the renal interstitium was even more messy.

Doctor Tang was taken aback again.

After careful cross-examination, it was found that the boy had no family history, no diabetes, and no underlying diseases. He also loved playing basketball and sports.

However, he is very different from other children. Because the family conditions are so good, his grandparents are keen to give him various supplements.

"My precious grandson, for more than ten years, has to eat a catty of walnuts, half a catty of red dates, 4 eggs, 2 cups of milk, 2 bowls of ginseng soup, and 5 spoons of black sesame seeds every day."

The child's grandfather said complacently: "I still have to drink Golden Partner, Life No. 1 every day, and this is not over. I also have to drink soft-shelled turtle soup once a month, and eat placenta once every six months."

"Eat some wild meat, wild venison, wild rabbit and other game from time to time, and seafood every night."

Doctor Tang was stunned for a moment, and fell into a kind of sluggishness, and it took him a long time to react.

After practicing medicine for more than ten years, it was the first time he saw such a weird parent, who was full of swear words and almost burst out.

No wonder teenagers have symptoms of kidney failure at such a young age.

It was really a disaster for ignorant and fearless parents.

He took a deep breath and said with a serious expression: "The child has a large amount of urine protein, and these high-protein foods should not be eaten in the future. Otherwise, the more you eat, the faster the disease will progress. If you don't control it well, you will soon die." It will progress to uremia and require dialysis...."

Before he could finish speaking, he was interrupted by his grandfather.

The old man snorted at his words and snorted coldly: "You are a doctor who knows nonsense. The child is so young and sick again. He must strengthen his nutrition. How can he eat less?"

"Besides, it's not too much to eat. I'm an old man, but he's so young. The more he eats, the better he will be, and the healthier he will be."

Doctor Tang asked unceremoniously, "How could the child be sick?"

The old man was stopped by the question, but he still insisted: "I will ask your doctor."

After finishing speaking, he turned around and yelled at the child's father: "I said that Huaxi is famous, and his medical skills are not very good. Take the child to Haishi to see a doctor quickly, and don't delay the child."

The child's father seemed well-mannered, maintaining a smile on his face, and asked Dr. Tang repeatedly instead of talking.

"Is the child's kidney disease caused by eating supplements? Doctor, are you sure? If it is confirmed, I will definitely give the child less food."

"This..." Dr. Tang was at a loss for words. As a strict doctor, although he was sure that these high-protein supplements ruined the child, he couldn't draw a conclusion directly. After all, the doctor has to bear the responsibility for every word he said. legal liability.

He could only repeat: "These supplements are excreted by the kidneys when you eat them. Since you have symptoms of kidney failure, you must not take them anymore. In the future, you should eat a low-protein diet to let the kidneys take a breath. Don't eat them again." It's such a heavy burden."

The child's father nodded, knowing what was in his mind, and turned around and said, "Dad, then listen to the doctor, eat less in the future, and arrange hospitalization first. If you need dialysis, we can take care of it."

Dr. Tang was quite satisfied with the parent's attitude. His heart moved, and he said, "I think the child is still young. As long as he doesn't continue to supplement with special supplements, there is still a possibility of recovery."

"By the way, Sanqing has a new drug for treating chronic kidney disease. It is in clinical trials. The effect of the drug is very good. You can try it. Maybe you can recover as soon as possible, and it won't be the turn of dialysis."

The child's father was instantly overjoyed: "That's great, thank you doctor, please arrange it quickly."

Doctor Tang smiled slightly, and said: "Then you must listen to the doctor's advice, and don't take any more messy supplements."

As he spoke, he shook his head with great emotion: "Hey, more and more young people are suffering from uremia nowadays, it is because they often drink beverages, take supplements, and drink messy soups, and the kidneys are damaged. gone."

"Among the patients I've seen this week, several of them have chronic kidney disease in their teens. They all have the same reason. The disease comes from the mouth. As parents, you must pay attention in the future."

The patient's parents nodded and said yes, and even the old man shut his mouth and no longer insisted on his theory of supplements.

After sending the high school students away, Dr. Tang saw several waves of middle-aged and elderly patients before ending his outpatient clinic.

In the next period of time, as he said, more and more young people came to see the nephrology department.

Moreover, when many people were diagnosed, they had already reached the middle and late stages and developed uremia.

This is from the onset characteristics of chronic renal failure, which is characterized by insidious onset. Chronic kidney disease stage 1-3 may not have any symptoms, and some patients who are careless or stubborn have no obvious discomfort even at stage 5. Call it a silent killer.

There is an inappropriate analogy, a dog that does not bark bites a person, which makes people hard to guard against.

To identify early, there is a very simple and economical method: routine urine test + kidney function test + kidney B-ultrasound.

According to the low price of tertiary hospitals: 7+20+80=107 yuan, once a year, no matter what kind of kidney disease can definitely be screened out early.

Unfortunately, many people do not have this awareness.

Because of another characteristic of chronic kidney disease, it develops slowly, so many people check up every year, even if the indicators are abnormal, the difference is not big, there is nothing uncomfortable, they are unwilling to treat, and even suspect that the doctor is deliberately scaring him, and then warm water Boil the frog, procrastinating beyond control.

When chronic kidney disease gradually develops into uremia, it will be too late!

When Dr. Tang saw young kidney patients, he would recommend them to participate in the clinical trials of Sanqing's new drug.

Because the young people are very sick, and they eat bad food, which leads to impaired kidney function. If they are treated early, the possibility of recovery is relatively high.

Unlike middle-aged and elderly people with chronic underlying diseases, even if there is a problem with the kidneys, it is necessary to treat high blood pressure, diabetes, etc. before they get better.

In comparison, young people are more effective and suitable for participating in clinical trials.

Facts have also proved this point. After two courses of treatment, the condition of the young patients who participated in the trial drug has improved, and it is getting better every day.