I can extract side effects

This strong impact reached its peak when Jian Jianyun saw the monkey playing games.

A macaque with a cute appearance, wearing a red cap, staring at the screen without blinking.

After the local mice emerged from the hole, they were smashed down by the stick again.

It would take a pine nut, stuff it into its mouth, poke its mouth, and look at the screen even more excitedly.

It can be seen that this simple game of exchanging a gopher for a pine nut made the monkey deeply intoxicated and unable to extricate itself.

And after discovering that you only need to use your brain, you can get delicious pine nuts.

The monkey even gave up the joystick and opted directly for stream-of-consciousness manipulation.

As for the free hands, they were used for eating pine nuts.

This dual-purpose multitasking method obviously satisfied both parties in the experiment.

Jian Lianyun observed carefully for a quarter of an hour before leaving the game room in shock.

"Wow, I've only read papers and some news reports on this topic before, but I never expected that when the brain-computer interface really appeared in front of me, it would be so cool, it's like a sci-fi movie coming into reality. "

She said full of praise: "I am full of expectations for this project now. I don't know when I can see it applied to the human body, so that paralyzed patients can also realize the freedom of games."

"Hehe, what we want to achieve is not just the freedom of the game." Chen Yiqing was very satisfied with her reaction and said with a smile.

Obviously, the wonderful performance of the stream-of-consciousness monkey left a deep enough impression on the proprietress.

If the proprietress knows, it means the boss knows.

This is undoubtedly a good thing for the project team.

"Okay, whatever you do, I'm very supportive."

Jian Lianyun's expression was still unfinished, and he hurriedly urged: "Is there anything I can use? I can't wait."

"There is just one thing that needs your help."

"After more than a month of hard work, we made a simple semi-invasive microelectrode implant that needs to be placed in a blood vessel in the monkey's brain."

"Wow, that's great, this is definitely my favorite operation." Jian Lianyun said excitedly, eager to try.

"Then go to the meeting room first and discuss the specific location of the blood vessels."

Chen Yiqing brought Jian Lianyun to a meeting room and met with the other three project team members.

So far, the entire core team has arrived.

After some discussion, the five people determined the position of the implanted blood vessel and came up with a preliminary experimental plan.

The monkey in the lab has had microelectrode arrays implanted in its cerebral cortex.

And they will re-implant this device in the large vein of the macaque's brain to obtain another kind of brain electrical signal.

Since it is different from the neural electrical signals obtained by direct implantation into the cerebral cortex, it is necessary to compare the neural signals obtained by the two methods, then analyze them through algorithms, and then convert them into the same digital electrical signals.

In this way, the accuracy of the signal can be greatly improved.

In the later stage, the direct signal connection on the top of the monkey's head will be disconnected, and only the vascular stent will be used to collect and transmit the signal.

If all goes well, the signal collected by both methods should achieve the same effect.

The animal experiment is only successful when the monkey can control the steel arm and play the game smoothly only with the vascular stent.

***

***

In the exclusive operating room of the neuroscience laboratory.

A cerebrovascular interventional operation is underway intensely.

The four of Chen Yiqing changed into surgical gowns, stood beside the operating table, and watched intently.

Jian Lianyun stood in front of the operating table, skillfully opened a small 2mm incision in the monkey's neck, and slowly passed a long microcatheter in.

Soon, the silver needle-sized microelectrode sensor coil was precisely implanted in the predetermined position through the jugular vein and the cerebral vein in turn, and was firmly fixed on the blood vessel wall.

Then, an extremely thin silk thread traveled through the monkey's cerebral vein and reached the jugular vein.

The silk thread is connected to a microchip the size of a fingernail, wrapped together in a biological protein material, and implanted into the subcutaneous tissue of the monkey's neck, forming a small bump.

"Sewing, call it a day!"

Jian Lianyun put down the surgical instruments and breathed a sigh of relief, feeling a little tired.

The monkey's brain is far less complex than the human brain, but she has just finished postpartum recovery, and the delicate brain surgery of more than an hour is also very exhausting for her mentally and physically.

Fortunately, monkeys, as the closest primate to humans, have been thoroughly studied by humans.

Dissecting monkey brains is a required course for every neurosurgeon.

So everything was not difficult for her, and it was even as smooth as killing a chicken with a sledgehammer.

"It would be great if human brain surgery was as simple as this, and it can be promoted quickly without too high a threshold."

Jian Lianyun couldn't help thinking, but in the next second, a burst of warm applause interrupted her thoughts.

She looked at the others, as well as her surgical team, and smiled expectantly.

"Next, it depends on the performance of the monkeys, maybe we will make history."

***

***

In the control room, on a huge experimental table, there are several computers on one side, and a row of monitors on the other side.

Wen Renlong quickly shuttled between the computers, testing their status. He likes to operate multiple computers at the same time, enjoying the feeling of numbers and letters flowing through his fingertips.

Zhang Li sat quietly on a chair, looking at the computer monitor intently, doing final adjustments.

Wang Dali was going in and out, checking the mechanical arms, joysticks and other equipment, to ensure that any problems could be solved as soon as possible.

Chen Yiqing stood upright, looking at the monitors carefully, observing the monkey's body language on the screen.

These monitors are installed in the game room, each of which is connected to a different camera, shooting the actions of the monkeys playing the game from different angles, and presenting it perfectly in front of everyone.

Jian Lianyun stood side by side with Chen Yiqing, also observing the monkey's movements.

Behind the control room, there is another industrial robot arm, which is exactly the same as the one in the next room.

The mechanical arm was motionless, the artificial elbow was slightly extended, and the two fingers were fully spread.

The whole shape is smooth and powerful, giving people a feeling of ready to go.

Those polished joints and silent motors seem to be ready to start at any time, making some shocking movements to accomplish a meaningful thing.

Wang Dali walked into the control room again, this time, instead of leaving quickly, he closed the door.

This seems to be a starting signal.

Chen Yiqing raised his head, looked at Wang Dali, and got a clear look.

Then, he made a start gesture and said in a deep voice.

"Everyone, after more than two months of hard work, it's finally time for the show."

"We have collected many nerve signals through cerebrovascular stents, and used different nerve signal data of the same action to run multiple versions of the linear regression algorithm. Finally, we found the optimal regression coefficient and made accurate trajectory predictions. , and converted into a digital electrical signal."

"Right now, the macaque is in the playroom, playing games as usual."

"At the same time, its brain movement control signals will be transmitted to the computer through two different sets of microelectrode arrays, and then converted into digital instructions, and then sent to the two robotic arms in the two rooms. "

"One of the sets is the cerebrovascular stent tested today. The nerve signals collected by it are wirelessly transmitted to the computer through the nerve chip in the neck."

"The other set is wired through a hat on the top of the head."

"The two systems also use different computers."

"But no matter which computer, it needs to convert the monkey's neuron activity into digital instructions and send them to the robotic arm within 200-300 milliseconds."

"300 milliseconds is the maximum time for the movement signal to be transmitted from the cerebral cortex to the limbs and start to produce movement. If this time is exceeded, the movement of the mechanical arm will not match the picture seen by the monkey, resulting in a slow-motion delay."

"We're going to first detect the trajectory of the robot arm, then compare them, see where there are gaps, and then make improvements."

"Okay, next, it's time to witness the miracle."

"let's start!"

With an order, Wang Dali turned on both brain-computer interfaces.

Everyone looked at the mechanical arm in unison, everyone looked extremely nervous.

The room was eerily quiet.

Nothing unexpected happened, but nothing happened either.

Chen Yiqing glanced anxiously at the monitor, only to see that the monkey was still playing its game, and the pine nuts were constantly being thrown into its mouth.

He looked at it for a few seconds, then shifted his gaze to the mechanical arm.

"Moved!"

Suddenly, I don't know who let out an exclamation.

Without any warning, the metal joints and rubber tendons of the mechanical arm moved, and two metal fingers firmly clamped a joystick.

The five immediately looked at the main screen of the computer, and saw two bright lines drawn at the same time.

The red line traces the movement of the monkey's own arm as it plays the game.

Green lines begin to trace the movement of the robotic arm, which appears to be trying to keep up with the movement of the monkey's arm.

In the first few seconds, there is a considerable distance between the two lines, which shows that the BCI's predictions are not very accurate.

But after a few minutes, they began to converge until the two lines almost coincided.

"Awesome!"

"It's done!"

"It's so cool!"

The five people shouted in surprise at the same time, and the room instantly became extremely noisy.

After a while, the lines have stabilized and barely change any more.

Chen Yiqing seemed to have discovered something now, and said with a puzzled look: "Huh? Why is there no line of the other arm?"

Everyone's attention was instantly shifted to the mechanical arm in another room.

Wang Dali dialed the phone and was quickly connected.

"Hey, did it move?" Wang Dali asked, wondering why the other party didn't show any excitement at all.

"No, it's as if it's dead, motionless." This is the lab colleague who was guarding over there.

"How could this be? Wasn't it good before, and our side is moving very well."

"That's the hell, my arm on this side is completely motionless, I can't even hear the sound of a motor, and my fingers don't bend at all." The other party's voice was full of frustration.

"That's not good, we have to move together to compare." Wang Dali was a little anxious.

As much as he tried to stay calm, he could still feel the tension in the room growing after listening to the conversation.

His mind was spinning rapidly, trying to find the answer from his past experience: "No, shouldn't you be in charge of this arm before? Is the indicator light flashing? Could it be that some part is broken?"

The other party was very depressed: "I also asked an engineer from your equipment department to do it. I majored in chemistry, and I learned some electrical knowledge by myself. If some parts are broken, how do I know this?"

Wang Dali was speechless immediately: "Are you sure you have checked every device? Have you checked the transmission line?"

"I checked. Before you called, I just checked all the equipment. Now I checked it again, but it still didn't work. Maybe something went wrong. After the experiment is over, I have to check it carefully."

There was a rustling sound on the phone. The other party seemed to be checking something, talking to himself, and his voice became flustered.

"I've restarted the device, tried everything, but it still doesn't work."

"What? What should I do?"

"Don't worry, slowly recall each step and see if you can remember anything."

Wang Dali tried his best to comfort the other party, racking his brains to think of every possibility.

Suddenly, a flash of inspiration flashed in his mind, and all the thoughts disappeared, leaving only one last thought.

Although he thought it was impossible, he was still going to try it.

"Well, if we can't find anything wrong, we usually check to see if the power switch is on."

As soon as the voice fell, a scream came from the phone.

"Oh my god, I just remembered, I forgot one thing, how could I not have checked this?"

"What? What did you forget?" Wang Dali asked eagerly.

"Nimma, I actually forgot to turn on the power switch of the mechanical arm."

A scream came over: "Move, move, finally move!"

"It moved, and this side also moved."

At the same time there was a shout from the room on this side.

Wang Dali immediately hung up the phone and looked at the computer screen.

The trajectory of the other robotic arm finally emerged.

This is a gray line, which, like the green line, initially tracks the movement of the monkey and then adjusts continuously.

The distance between the three lines quickly narrowed, they converged together, and slowly, completely overlapped into a colorful line.

Thick lines, short trajectories, but a bold journey through the history of neuroscience.

At this momentous moment, everyone's thinking froze.

The eyes looking at this colored line instantly became extremely hot.

It was as if a giant dragon was looking at a rare treasure, with flames flowing in its eyes.