Into Unscientific

  Chapter 56 Are you a devil?

  When the female Periplaneta americana burped, it had been more than an hour since the cockroaches ate the glue bait for the first time.

  So apart from this unlucky egg, the first batch of cockroaches that ate the gel bait also responded one after another.

  In the containers No. 1-3 at this time, you can clearly see several piles of cockroaches gathered together, rustling and having a carnival.

   In stark contrast to this, is the scene in container No. 4-6:

  After more than forty minutes, even in the No. 4 container with the best medicinal effect, there are only five or six cockroaches in a hyperactive state.

   Then another hour passed.

  In container No. 2, the males who ate the female cockroaches also began to appear abnormal one after another.

  At the same time, due to the dissipation of pheromones, each male cockroach is surrounded by multiple female cockroaches.

  The corpses of the male cockroaches also became the belly of the female cockroaches.

  Then these female cockroaches dispersed one after another, and the next round of transmission continued again and again.

  Eight hours later.

   Only a few of the cockroaches in containers No. 1-3 still showed signs of life, and the rest were either mutilated corpses or complete hiccups.

  In the No. 4 container, there are only about ten dead cockroaches, and the number of cockroaches in the state of hypertoxicity is about fifteen or six.

  As for containers No. 5 and No. 6, let alone the number of deaths in single digits.

  Seeing this situation, Tang Yiqiu, the youngest among the crowd, couldn't restrain his emotions, and immediately said 'yeah':

   "Senior, it seems that our experiment was very successful!"

  As a senior student, this is the first time she has participated in a project of this level. Seeing the results of the research group, how can this little girl not be excited?

  But to her surprise, Xu Yun shook his head slightly:

   "Success? Xiao Tang, this is not considered a success. It is true that we have developed the fourth-generation imidacloprid, but is it really the perfect form of imidacloprid?"

  Seeing that the school girl was a little confused, Xu Yun pointed to the biological container and said:

   "Let me ask you, what did the cockroaches do after eating the corpses of the same kind during the experiment just now?"

   Tang Yiqiu blinked because she didn't understand, and subconsciously replied:

   "The nerves are excited, and then emit pheromones to mate with cockroaches of the opposite sex."

   "Look, isn't this problem coming?"

  Xu Yun clapped his hands and said with a smile:

   "The biological container we prepared has a limited volume, which causes all the cockroaches in it to be covered by pheromone, and then they will have mating behavior.

  But in the living environment, the range of activities of cockroaches is not limited to such a small container?

  Their biological density may not be comparable to that of the container, but the complexity of the travel route and smell crossing is higher than that of the container. This is the difference between the experimental environment and the real environment. "

  Tang Yiqiu nodded half-understood, flicked her ponytail behind her back, and asked:

   "So Senior Xu, are you planning to improve the pheromone protein and expand the spread of pheromone?"

   "No, no, you misunderstood me."

  Xu Yun quickly shook his head and said:

"I mean

  According to our existing imidacloprid formula, if a male cockroach A only attracts female B before death, what happens if one or several male C pass by at this time?

  If you are lucky, C may wait for B to be attracted by B's pheromone after mating with A, and then mate with B to be poisoned.

  But there is a time for the onset of the drug. What if C goes away during the incubation period of the drug?

   Isn't this likely to cause a considerable part of the target to be unable to be covered? "

  Looking at Tang Yiqiu and the others with blank faces, Xu Yun smiled happily:

   "So. Can we add a lure to the pheromone protein, so that the pheromone emitted by the cockroaches that gnaw for the first time is not divided into male and female, so that A can attract C, that is

   A and C mate, or what about males exchanging lymph fluid? "

  After Xu Yun finished speaking, the whole laboratory suddenly fell into silence.

   After a few seconds, the girls Tang Yiqiu and Zhou Peiyao said in unison:

   "Senior, are you a devil?!"

  Xu Yun shook his head and explained with a serious expression:

   "No, no, no, this is just a logical supplement from a realistic point of view.

  After all, we have a biological model as the basis—in a standard residential area of ​​one kilometer, the number of daily interactions of same-sex cockroaches is only 0.37.

  So the situation I mentioned is very likely to happen in reality.

  Besides, if we can solve the problem of lures, we may even develop corresponding insecticides for mosquitoes and flies in the future, which is also a very broad space. "

  Xu Yun's words are very confident, because one of the core points of the fifth-generation imidacloprid formula he obtained is that it can produce specific lures through cell fusion, thereby promoting the cognitive disorder of cockroaches.

Of course.

  It also contains Yidiandian's personal emotions, which will not be shown here for the time being.

   Then Xu Yun paused, and said seriously:

   "Finally, there is the issue of insecticidal efficiency. Although our fourth-generation imidacloprid is much faster than the other three gel baits, I think the binding speed of the target protein is still a bit slow.

  Considering the attractive effect of living body movement, I personally feel that 20 minutes for the first-generation body and one hour for the second-generation to fifth-generation bodies, which should be considered a reasonable configuration.

  Because cockroaches will attract the same kind to eat after they die. "

  Previously considering that the research team had not even successfully developed the fourth-generation imidacloprid, Xu Yun retained some optimization directions for the fifth-generation imidacloprid and did not announce it.

  After all, the fourth generation has not yet broken through and the fifth generation is too ambitious.

  But now with the technological breakthrough of the fourth-generation imidacloprid, some of his ideas can be put on the table:

   "For example, the target of imidacloprid is nAchR, which is the R81 arginine residue in the LoopD region of the β1 subunit, and the binding time is generally not less than 30 minutes.

so.

  Can we add some other ideas?

  Such as inhibiting acetylcholinesterase, or acting on sodium channels? "

  Looking at the contemplative crowd, Xu Yun continued:

   "Mammalian sodium channels have 9 subtypes, namely NaV1.1-NaV1.9, and the subtypes of insects are more complicated, and the binding formula of the receptor also needs to be deduced by us."

   "However, we have passed the most difficult threshold of serialization, and the rest of the link will undoubtedly be much easier, so everyone, please work harder?"

   "Strive for the cockroaches to ascend to heaven as soon as possible!"

The second chapter may still be at three or four in the morning, and after the second update, there will be a testimonial on the shelves. It will be updated in one breath after 12 o'clock tomorrow night. I originally planned to go back today, so I directly found a hotel to stay and code all night. !

  (end of this chapter)