Xueba's Black Technology Simulator

Biological experiments are very boring, dealing with various solutions, reagents, and test tubes.

Because Lu Xiao had an accurate extraction method, he directly split the steps, and more than a dozen people did the experiment separately.

Although this is an official laboratory, the people inside should also be trustworthy.

But the heart of defense is indispensable, and we still have to keep a hand.

The most critical liquids were made by Lu Xiao himself. Only in this way can we ensure that the technology is in Lu Xiao's hands.

Of course, there will definitely be problems with the final ownership of the things made in this laboratory.

So before starting, Lu Xiao asked how to calculate the results before doing it.

The experimental project that solved the key problem, as well as the current stem cell project, were all made by Lu Xiao, and the technology naturally belonged to Lu Xiao himself.

Because I didn't spend a penny from the laboratory, and I didn't use anything from the laboratory.

But with the things in the laboratory, although Lu Xiao put in the main intellectual labor, the final result is definitely not Lu Xiao's own.

So in order to distinguish, Lu Xiao actually separated the stem cell project from the laboratory.

Although he also has a laboratory, his own laboratory has not been built yet.

Now that he came to Jiangcheng, he was renting the Jiangcheng laboratory.

All materials and labor costs for this project are also responsible for themselves.

Lu Xiao calculated that it would cost hundreds of thousands.

Even if it is one million, if there is more in the end, it will be regarded as rent for Jiangcheng Laboratory.

This is the only place in the mainland where such a high-level experiment can be done.

In fact, there is no use here at all in the early stage, because the crisis has not yet appeared, and there is no need to study very dangerous microscopic organisms.

It's just that he has been appointed to work here, and he is still allowed to transfer people, so it doesn't count too much.

Stem cell technology also has the potential to be commercialized.

The other technology obviously has flaws and the flaws haven't been solved yet, and it may also be a technology that solves a big crisis. Lu Xiao regards it as a contribution and gives up the ownership.

In this kind of big project that benefits the country and the people, a few students from big bosses are invited, which is impossible to invite under normal circumstances.

If Lu Xiao still had the cheek to say that it was all due to him, that would be too thick-skinned.

On the third day of the experiment, basic preparations were still being done.

The people invited in the capital last time have already arrived.

They can do the preparatory work first. Lu Xiao's main purpose is to study the technology of genetic evolution, and use this method to solve the big crisis at the end of the year.

Arrange their work first.

Among them, Zong Lao's apprentice Sang Lin and Lu Xiao made him the deputy team leader of the new project because Sang Lin is very experienced.

He is also the core member of Zong Lao team.

Elder Zong estimated that he was also studying preventive measures in a secret base, and Lu Xiao was also very critical here, so he sent his eldest disciple over.

Sang Lin's major is mainly in the respiratory system, which has nothing to do with the human body evolution project.

But you must know that the key reason for general respiratory diseases, such as colds and sneezing, is the entry of germs into the body.

So Sang Lin naturally knew a lot about B poison.

Moreover, Lu Xiao's technology also uses the B virus to copy other genes into the human body. The ultimate goal is to improve the human body and make people stronger.

At first, Lu Xiao thought he had succeeded, but in the dungeon, he faced countless people chasing and intercepting him.

Originally, there was hope to escape, but in the end, because he wanted to obtain technology simply, he chose to surrender voluntarily.

But unexpectedly, a month later, this technology would actually mutate the gene.

This is very uncomfortable.

Foreign experts in Dungeon World have tried but failed to find a solution. Lu Xiao can only place his hope on domestic experts and himself.

Stem cell technology, that has to stand aside, the most important thing is to study now.

After Sang Lin came to the laboratory, Lu Xiao immediately approached him to communicate with him about the project.

After listening to Lu Xiao's solution, Sang Lin felt a little ridiculous.

He thought he was here to study specific medicines or vaccines, but it turned out that he started with the most fundamental genes of the human body!

This is like playing a game. It was originally a difficulty of 50, but you have to choose a difficulty of 99.

The complexity of genes is countless times more difficult than researching y vaccines and specific medicines.

What kind of Bacterial virus samples are there in Jiangcheng's laboratory? These things can only be tested here.

In the past, some samples were stored in underground secret bases. This time, because of the establishment of the laboratory in Jiangcheng, there was finally a research base on the surface.

After listening to Lu Xiao's general introduction, Sang Lin wondered: "Director Lu, are we starting from scratch? I'm afraid it's impossible to make it in time. Back then, the Human Gene Project took how many years to complete the sequencing, and we didn't have enough manpower. Anyhow, a crisis can happen at any time."

If Lu Xiao already had some technical foundation, then Sang Lin would naturally not raise any opinions, as long as he cooperated.

But if Lu Xiao didn't have anything, he wouldn't be able to do anything.

In the end, he was just directing blindly, and Sang Lin had to worry about everything, so he would definitely not be able to cooperate.

Lu Xiao knew the worry in the other party's heart and explained: "Don't worry, I already have the relevant technology here, but the current technology has a fatal flaw. While transforming the gene, it will also mutate the gene. I need to use it in reality. Experiment a few times to see if it is the same as what I thought."

Sang Lin wanted to complain, but he didn't know how.

You don't need to understand the magic of Lu Xiao, as long as you are using your mobile phone and computer, you can probably think of something.

Ordinary people think that Lu Xiao is the spokesperson of a special organization, and the technology is all researched by other people.

Sang Lin is different. He has been involved in many projects, and has been to many laboratories with high confidentiality with his teacher.

Even the most powerful group of biological experts, he knows.

He probably understands even some undisclosed experts.

Because it is definitely impossible for ordinary people and foreigners to know about these experts, but Sang Lin is an old student of Zong, and top experts also need to exchange knowledge.

In this way, he, an old student of Zongzong, gradually came into contact with some people that ordinary people don't know.

Since these people have never talked about such a project, it can be proved that the technology Lu Xiao obtained was not obtained from a secret laboratory in China.

If it is obtained abroad, it feels unlikely.

Then it is really the same as what I talked with the teacher before, Lu Xiao is really a variety of techniques simulated in his mind.

Looking at Lu Xiao, who is less than 20 years old this year, Sang Lin stroked his hair that had already gone gray when he was only 40, sighed in his heart, and decided to cooperate with all his strength.

He said: "That's good. Since I already have a technical foundation, I will fully cooperate. I don't know what I need to do now?"

Lu Xiao had known for a long time that the people sent by the big bosses would naturally not oppose him.

Otherwise, these people would not be allowed to come.

They were here to assist Lu Xiao. Lu Xiao didn't intend to hide this skill, so he began to tell the details without reservation.

"First of all, we need some excellent genes. These genes are preferably those of people with strong immunity. We can actually do a lot of things with this technology."

"For example, in the future we can choose the genes of athletes to bring their talents to more people, and we can also find the genes of scientists. Although many of them have achieved achievements through hard work, most of them are actually gifted. talent, such as a particularly good memory.”

Before Lu Xiao finished speaking, Sang Lin smiled and said, "Director, your genes must be the best!"

"Hahaha, let's study it later." Lu Xiao was very happy to hear other people's praise, and replied casually.

It seems that Sang Lin is not a very rigid scientific research worker, but more like some scientific research workers engaged in administrative positions.

Lu Xiao doesn't care whether his skills are good or not. They don't need to innovate in the early stage, as long as they cooperate.

"Continuing to talk about technical issues, gene evolution stems from the b virus that transcribes excellent genes into other genes in our body, preferably into bone marrow cells. As long as the most core cells are changed, there will be more and more changes over time. The more cells become newer."

Sang Lin probably knew why the gene was mutated, it was a change in the bone marrow cells.

Or use the b virus to modify the gene.

Naturally, this technology is not unfamiliar. Gene editing technology appeared in the Eagle Country a few years ago.

It is to use the special mechanism of archaea to complete the gene re-editing.

Now it seems that this technology should be upgraded again to directly act on the core cells, or it should be changed in large quantities to finally achieve the goal of human evolution.

Genes are extremely complex, and the biggest problem with the previous gene editing technology is still gene mutation.

So this technology is rarely used in humans.

Sang Lin is half a biologist, half a medical scientist, and knows a little bit about everything.

He knew that cancer was about to be broken, and there were domestic laboratories doing animal experiments, and human experiments were also on the agenda.

The general technical idea is to use genetic modification to activate the recognition ability of T cells in the human immune system, so that T cells can accurately detect cancer cells and activate autoimmunity to "clear" cancer cells.

The difficulty of this technique is that there are countless white blood cells in the human body, and it is impossible to activate only one, so let this one T cell kill the cancer cells.

Therefore, a large-scale exchange of blood is required.

The white blood cells in the replaced blood have to go through a very complicated and cumbersome large-scale white blood cell upgrade.

At present, there is no good way to upgrade, all are to slowly modify the gene, and then put it back into the patient's body.

Sang Lin had contact with the opposing team during a study tour, and finally talked about the future use of it.

When experimenting, naturally no matter the cost.

But these are all production costs, and they must be accounted for in the final customer use.

After roughly doing the calculations, a conclusion is drawn.

Treating cancer in this way requires about one million courses of treatment.

It doesn't have to be a complete cure, and it has to be a specific cancer.

Because some cancer eradication methods, that is, the gene that activates white blood cells, have not been found yet, and further research is needed.

But the good news is that this technology may be available in a few years.

The bad news is that only a small number of blood cancers can be cured, and they are extremely expensive.

After listening to Lu Xiao's introduction, Sang Lin suddenly realized that if Lu Xiao's technology is real, it can be used in cancer treatment.

"Director Lu, have you heard of CAR-T therapy?" Sang Lin asked.

This is also a test of Lu Xiao's level.

Let Sang Lin be able to judge whether Lu Xiao memorized the materials by rote, or whether he has deep attainments in the fields of biology and medicine.

Lu Xiao naturally knew about this therapy.

You must know that he is suffering from cancer in the dungeon world.

Of course, he needs to be exposed to various treatment plans, and Lu Xiao is a person who never forgets. From the various technologies that have appeared in front of him, he will use the ability of "photographic memory" to store them.

Lu Xiao smiled and said: "You are talking about Chimeric Antigen Receptor T, chimeric antigen receptor T cell therapy, right? I remember that in 2012, the first cancer patient cured by this therapy appeared abroad. Everyone is still alive."

"Ah, that's right, that's right, I didn't expect Director Lu to know all of this. You are so knowledgeable and memorized." Sang Lin praised.

Seeing that Lu Xiao was smiling when he heard his praise, Sang Lin continued: "In fact, we have also learned this method in China. The people in Ruijin Hospital in Shanghai are doing research, and clinical trials will be done soon. They are now drawing large quantities of blood. To modify white blood cells, if you use your method, can you let the b poison do it."

"Won't that save a lot of cost?"

Lu Xiao knew about this, because the project had been successful before he traveled.

It was in the headlines at the time.

It takes 1.2 million Xia Yuan to treat cancer.

Lu Xiao seems to remember that lymphoma was cured.

"You are right. The technology I have now can be used in many places." Lu Xiao said with certainty.

Sang Lin suddenly became excited.

To know this technology, it also won the Nobel Prize last year.

Of course, it is not the technology to treat cancer, which was successful in 2012, but the immunotherapy used in this treatment plan.

In 2013, immunotherapy was named the most important scientific breakthrough of the year.

In 2018, immunotherapy won the Nobel Prize.

What makes Sang Lin particularly regretful is that it is still too late for him to come into contact with this technology.

Or Xia Guo came into contact with this technology too late.

As a result, a large number of patents for this technology are currently in the hands of foreign people.

Take CAR-T therapy as an example, why is it so expensive?

The raw materials required for the preparation of CAR-T therapeutic products are obtained from each patient's own cells. This tailor-made personalized drug has everything from the collection and transportation of cells to the cultivation, storage, and quality control of the entire technical background. very demanding.

This also means that the production cost of the whole process is very high, so the cost will not be diluted gradually due to the increase in sales volume.

Moreover, the long-term research and development costs have to be allocated to each needle.

Of course, if Lu Xiao came up with another set of techniques now, he could completely achieve the same therapeutic effect, and he could charge as much as he wanted, and the cost was almost the price of cabbage.

At that time, many foreign companies may even go bankrupt.

Xia Guo's cell therapy has limitations.

Because the raw materials are expensive and highly dependent on imports; the virus coating ability is poor; there is no or less independent intellectual property rights, etc., so the final cost can only be more than one million per injection.

A lot of the money has to be paid to foreign countries as patent fees to buy foreign materials.

Who told us not to be the first to develop this technology.

Now Lu Xiao is researching the project of genetic evolution, but Sang Lin discovered that this project can take a shortcut and surpass another leading foreign technology.

Even if the project fails in genetic evolution, Sang Lin feels that as long as it makes progress in immunotherapy, it will be enough.

As for the big crisis, Sang Lin believed in the teacher even more.

With teachers around, the sky cannot fall.