I can extract side effects

Suzhou University, Sanqing Branch.

"Haha, Xiao Du, come in quickly, I have something to look for you."

In the dean's office, Du Biao received a warm welcome as soon as he appeared.

He was instantly flattered by Dean Lu's enthusiasm.

"Dean, what do you want from me?"

"I heard that the xenotransplantation operation in your laboratory was successful?" Dean Lu asked curiously.

"It can't be said that it was completely successful." Du Biao was habitually humble, and suddenly remembered that he was here to announce the good news, so he couldn't be too low-key.

So he quickly said: "We transplanted the genetically modified pig kidneys and islets into baboons, and the survival time is more than a week, which shows that the operation is quite successful."

"The baboons are very healthy so far, there is no acute immune rejection in the body, and all physical indicators are normal."

"This is the first multi-organ xenotransplantation in China, which is of great significance and has achieved zero breakthrough."

"Even in the field of xenotransplantation in the world, our pigs have the most modified genes, up to 36, and they are all perfect without any mutations or abnormal functions."

"The success of this operation is enough to prove that my country has reached the international leading level in xenotransplantation."

Speaking of this, Du Biao couldn't help but blush. Fortunately, his face and eloquence have been tempered by academic conferences, and he has already been reborn. He said these words in one breath without any pause.

Dean Lu slapped his thigh fiercely and applauded repeatedly.

"Okay, okay, okay, with such impressive results, it is only possible to apply for outstanding young talents."

"It seems that the school is really going to give you a hand this time."

Du Biao was overjoyed immediately: "Dean, you, you also like me?"

Dean Lu's face was serious, and he said: "Don't think that I always like to joke with you, but this time I really like your project."

"Xiao Du, I don't know whether I should praise you for your determination or your luck."

"The field you chose is really unpopular, and there are no competitors at all."

"Before you, it's not that no one has studied this area, and there are also big shots in this area, but the results are still a little bit behind compared with foreign countries."

"Besides, he's getting older, so he's going directly for the academician. There's no conflict with you at all. Instead, he has broad prospects for cooperation."

"I've come to this point, you go back and think about it yourself."

"Research on xenotransplantation, I remember that there was the first clinical case of pig heart transplantation in a foreign country, and it started to become popular. Before that, it was all clinical research on non-primates, and it has not been applied to humans."

"You are really lucky. As soon as you become popular, you will produce results."

"Now this piece is not only very popular, but also extremely hot. According to my gossip, it's even on the Ministry of Science's focus list."

"Your current research can be regarded as filling the clinical gap in domestic non-primate research. Not only is it multi-organ transplantation, but also the modification of 36 genes, which can be regarded as solving some of the problems of immune rejection and biosafety."

"I went back to the meeting yesterday, and Academician Meng asked about your project."

Du Biao was taken aback: "Ah, what did Academician Meng say?"

"As you know, we have 9 academicians at Gusu University, mainly in two areas, half in the field of medicine and biology, and the other half in the field of nanomaterials."

"The four medical academicians are all very interested in your project."

"That's why I said, you have great hopes for Shen Jieqing this year."

Dean Lu said with a smile: "Has the paper been published? This is very important. I guess your paper must be published as a regular issue, so the hard conditions are met."

Du Biao was a little embarrassed: "It hasn't been published yet. I just wrote the first draft and am waiting for the survival data of baboons."

Dean Lu waved his hand: "It's okay, it's still early."

"Your monkeys just need to survive for more than 40 days."

Du Biao nodded, and then asked curiously, "Why 40 days? Is there anything special about it?"

At the same time, I wondered, should I terminate the experiment after 40 days? Or keep the baboons alive?

Dean Lu shook his head, a smile slowly appeared on his face.

"Because the boss who did the xenotransplantation also did pig kidney transplantation, but the recipient monkey only survived for 38 days. As long as you surpass him, it will be considered a breakthrough. Hahaha~"

Du Biao couldn't help smiling: "Then it shouldn't be difficult. I'm very confident in the vitality of the baboons. They must survive for more than 3 months."

"Yeah, that's better, it's directly at the international leading level." Dean Lu laughed heartily.

"The school told me privately that it has put you on the list."

"Hurry up and write the PPT of the speech. Remember to be concise and concise. Don't write thirty or forty pages. The judges don't have time to listen to you so much. Just write a dozen pages, put the paper on it, and explain the project clearly."

"Well, I understand. I'm already writing." Du Biao was secretly happy and nodded quickly.

"That's good." Dean Lu taught earnestly, without any secrets.

"Don't worry, if it's other subjects, laymen may not be able to understand the subject, but for your subject, even elementary school students can understand it, let alone the group of academicians and outstanding young people."

"Anyway, your meal is already on the table. For the next thing, remember to draw more cakes. The bigger the cake, the better. Those old men will eat this."

As Dean Lu talked, he couldn't help falling into memories.

"When I was in the meeting back then, those guys asked me what was going on. Yes, they rarely asked me about the specifics of the project, so they caught me and asked..."

"What is the biological significance of your project?"

"Is there any deep medical problem solved?"

"Many of the papers you publish and the work you do are hot issues. The articles are good-looking, but what human problems are fundamentally solved?"

The more Dean Lu said, the more angry he became: "Ah, these questions, looking tall, are actually all nonsense."

"I was almost dumbfounded when I was asked on the spot."

"Fortunately, I am clever and have a solid background in biology. I quoted extensively on the spot, quoted scriptures, and talked from biology to anthropology, and then to philosophy. I finally fooled these old men."

Hearing these words, Du Biao became more frightened: "Huh? The judges ask this kind of question? Then I have to write it down."

He groped around and found that he didn't bring a notebook, so he quickly took out his mobile phone, opened the memo, and wrote down all the questions Dean Lu said one by one.

After talking so much in one breath, Dean Lu also felt a little dry, so he picked up a glass of water to moisten his throat, and continued.

"However, your research is not the same as mine. The illiterate can make up a lot of brains after reading it."

"You can talk about it in a big way. Not only has it solved the major medical problem of organ transplant shortage, but it has also made a new elaboration from the perspective of genomics and biogenetics, at a deep level, and from multiple perspectives."

"It is of epoch-making significance to the survival of mankind and the continuation of civilization."

The more Du Biao listened, the more confused he became: "Is my research really so significant?"

"Is it such a great contribution to mankind? Can it even affect the entire human civilization?"

"It doesn't matter how meaningful it is to human beings, but it is very important to tell everyone." Dean Lu made a final decision and made a key summary.

"In short, this ppt is related to your bright future, so you must not be careless."

"You'd better find someone who can write to write. You must highlight the highlights of your work. After you write it, show it to me. I will check it for you."

"Also, it's better to publish your paper as soon as possible, and don't delay it too late. The monkey can die at any time, and it won't be a few days later."

In the end, he still didn't forget to mention Du Biao, he gave it all.

"Understood, thank you Luyuan. Don't worry, I will never let you and the school down."

Du Biao was confused, but he also wrote down one by one, and nodded firmly.

It's just a ppt, Du Biao still has a certain degree of confidence in his ability to write documents.

Since the school has made it clear that it will support him in his position, he has a great hope of being selected as a young scholar.

This is the case when evaluating hats. It depends not only on the ability of the judges themselves, but also on the connections behind them and the support of the platform.

In the case of having all three, losing the election is unlikely.

His application has been submitted long ago, and it describes the research work to be carried out, mainly focusing on xenogeneic organ transplantation, including solving a series of clinical problems in the human body. In China, it is definitely very innovative.

And the application of outstanding youth is all operated through the unit.

The academic committee of the unit selects the list of the best, and then the unit signs the recommendation and submits the materials to the corresponding science department.

Therefore, the strength of the platform and the bosses behind it play a decisive role.

Suzhou University has its own academicians, and they are also academicians in medicine and biology. In addition, there are more than 30 outstanding young people.

These contacts are very important to him.

Especially in the selection of medicine and biology, the competition is all about connections.

Although the academicians and outstanding youths of the school had to avoid during the selection conference, it was still very easy to say hello to familiar colleagues and exert influence.

From the tone of the school, it is obvious that the high school is also very interested in the emerging field of xenotransplantation, and wants to train a young academic leader.

Then, besides him, there is no other choice.

In addition, his academic achievements are indeed outstanding, and no one can deny it.

It is still an unpopular track that has just warmed up, and there are not many competitors.

It can be said that the right time, place and people are in harmony, and all of them are in place.

If this still doesn't qualify him as Jie Qing, then he might as well go home and find a piece of tofu and beat him to death.

"That's good, by the way, many students are interested in your research direction this year, and the school has added a lot of student places for you."

"Here is a list, and there are a few direct descendants of big bosses who want to come to you to study for a doctorate."

At the end, Dean Lu picked up a document from the table and handed it over.

Du Biao shuddered, knowing that this was the so-called exchange of benefits.

He took the list with a heavy heart, roughly scanned the names on it, and still had some doubts in his heart.

"What is the ability of these people to do research?"

"If it's really limited, it's not easy to do gold plating on scrap iron."

Dean Lu seemed to see what was going on in his heart, and smiled and said, "Don't worry, I'll check everything for you."

"There are parallel imports in there, but not many, just one or two. The others are capable, you just need to train them well, don't worry too much."

"They are also opening up a new direction for the boss. After all, the mainstream research fields are almost on the way."

"Now seeing such a brand new virgin land, everyone will be tempted and want to get a foot in it."

"Even if you can't make any academic achievements, you can make a lot of money by starting an organ transplant company."

"The relationship here, as long as you know it in your heart."

Du Biao nodded slowly, without saying anything.

He knew in his heart that this was the price he had to pay in order to be selected as a outstanding young man.

After putting on the hat and getting on the poker table, the days to come will be much better.

Criticize the schoolboy, envy the schoolboy, understand the schoolboy, and become a schoolboy.

At this moment, Du Biao suddenly understood everything.

*****

Kunming, Animal Experiment Center.

"What? The baboon is dying?"

"what happened?"

Huang Qin rushed into the cultivation room with a stride, shouting eagerly.

In the cultivation room, several large cages were separated by fine barbed wire, and the six baboons who had undergone transplantation were locked up.

At this moment, in the cage on the left hand side, a baboon was lying on the mat, with its feet up in the air, motionless, and looked like it was dying.

"45 days after the kidney transplantation, the condition suddenly took a turn for the worse. The left kidney stopped producing urine and could not clear the creatinine in the blood. After a biopsy of the transplanted kidney, it was found that the glomerular cells in the left kidney were necrotic, and there were microscopic thrombus formation for unknown reasons. .”

Xiao Gao followed closely, explaining in a hurried voice.

"We're still researching this, and it's not clear why there is a difference in urine output between the two kidneys, or why creatinine isn't being cleared."

"One guess is that both humans and baboons have higher blood pressure than pigs due to upright walking, so the blood vessels of pig kidneys may be damaged by the blood pressure of baboons after transplantation, resulting in damage to the vascular endothelium and blockage of blood vessels, thereby triggering blood clots. "

"In addition, since the immunosuppressants we use are all drugs for human use, long-term use also has many side effects on baboons, which may have caused some damage to kidney function."

"Combined for all reasons, this baboon will most likely not live for a few days."

When Huang Qin heard this, his expression softened a bit: "That's it, there's nothing I can do about it."

"Xenotransplantation is still a new research, and it is still full of many unknowns, waiting for us to answer."

"It seems that more clinical research is needed to solve a series of problems caused by xenotransplantation, so as to truly benefit mankind."

He glanced at the baboon's painful expression, and immediately made a decision.

"Since it's hopeless, let's euthanize it. It's also considered to be an end, and it's in compliance with the regulations."

"By the way, how are the other baboons doing?" He asked as he walked to the other cages.

Seeing this, he couldn't help frowning.

There were 5 baboons left, each with its own abnormality, some were slow and listless, some were grinning and irritable, in short, few of them looked healthy.

"These five are also in certain physical condition," Xiao Gao rushed over, and when he saw the situation, he hesitated to speak.

"It's okay, just tell me carefully." Huang Qin comforted: "Scientific research is always full of various accidents, and it is impossible to follow the plan completely."

"Even if all the baboons are dead, it's expected, but we need to delay their death as long as possible, you know."

"As long as the cause of death can be found, and the next experiment continues to improve, it will be considered a huge gain."

Xiao Gao nodded and told the situation one by one.